3,4-Difluoro-5-(pentyloxy)benzoyl chloride CAS 1443339-74-9
| CAS No. | 1443339-74-9 |
| Molecular Formula | C12H13ClF2O2 |
| Molecular Weight | 262.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 3,4-Difluoro-5-(pentyloxy)benzoyl chloride (C12H13ClF2O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
3,4-Difluoro-5-(pentyloxy)benzoyl chloride (CAS 1443339-74-9), molecular formula C12H13ClF2O2 and molecular weight 262.68 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3,4-Difluoro-5-(pentyloxy)benzoyl chloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H13ClF2O2 |
| Molecular Weight | 262.68 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F/Cl-containing |
Related Difluoro Standards
- 3,5-Difluoro-2-(isopentyloxy)benzoyl chloride (CAS 1443309-66-7)
- 3,5-Difluoro-2-(pentyloxy)benzoyl chloride (CAS 1443335-72-5)
- 2,2-difluoro-2H-1,3-benzodioxole-5-sulfonyl chloride (CAS 313681-67-3)
- 2,6-Difluoro-4-(5-propylpyrimidin-2-yl)benzaldehyde (CAS 574705-83-2)
- 3,5-Difluoro-4-ethoxybenzophenone (CAS 951884-68-7)
- ethyl 6,8-difluoro-4-oxo-chromene-2-carboxylate (CAS 2170697-46-6)
- Methyl 3,5-difluoro-4'-methyl-[1,1'-biphenyl]-4-carboxylate (CAS 2635937-72-1)
- 951884-66-5 3,4-Difluoro-4'-ethoxybenzophenone MFCD09801564 (CAS 951884-66-5)
Recommended Standards
- N-Benzyl-4-chloro-2-nitroaniline (CAS 10066-18-9)
- N-(2-amino-5-chlorophenyl)-4-hydroxybenzamide (CAS 1016495-74-1)
- 5-Chloro-1-cyclohexyl-3-(difluoromethyl)-1H-pyrazole-4-carbaldehyde (CAS 1411531-45-7)
- 3-Chloro-4-hydroxy-N-(5-methylpyridin-2-yl)benzamide (CAS 1017109-71-5)
- Octyl L-alaninate (CAS 63907-63-1)
- 1-(Phenylethynyl)-4-styrylbenzene (CAS 21850-30-6)
- 3-(2-Aminoethyl)-7,8-dimethylquinolin-2(1H)-one hydrochloride (CAS 1266686-95-6)
- Methyl 16-oxohexadecanoate (CAS 45247-78-7)
- Paliperidone Impurity 126 (CAS CATO-C4X-1724126)
- 6,8-Difluoro-2-propylquinolin-4-amine (CAS 1189105-83-6)
- 1,7-Hexadecadiene (CAS 125110-62-5)
- 6-benzyl-3-thia-6-azabicyclo[3.1.1]heptane (CAS 1638760-83-4)
- 5,6-dihydro-4H-1,3-thiazin-2-amine hydrobromide (CAS 2799-75-9)
- Semaglutide impurity 59 (CAS CATO-C4X-222659)
Why CATO?
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