Methyl 2-(3,4-difluoro-5-methoxyphenyl)-2-oxoacetate CAS 1443344-83-9
| CAS No. | 1443344-83-9 |
| Molecular Formula | C10H8F2O4 |
| Molecular Weight | 230.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies Methyl 2-(3,4-difluoro-5-methoxyphenyl)-2-oxoacetate (CAS 1443344-83-9), a certified reference material (molecular formula C10H8F2O4, MW 230.16 g/mol) for analytical method development and quality control.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, Methyl 2-(3,4-difluoro-5-methoxyphenyl)-2-oxoacetate is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 230.16 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), Methyl 2-(3,4-difluoro-5-methoxyphenyl)-2-oxoacetate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H8F2O4 |
| Molecular Weight | 230.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
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Recommended Standards
- 2-[4-(Carboxymethyl)phenyl]-2,2-difluoroacetic Acid (CAS 1436389-36-4)
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- 3-Phenethyl-5-((1-phenyl-3-(p-tolyl)-1H-pyrazol-4-yl)methylene)-2-thioxothiazolidin-4-one (CAS 313049-95-5)
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- N-(4,5,6,7-Tetrahydrobenzo[d]thiazol-2-yl)-2,3-dihydrobenzo[b][1,4]dioxine-2-carboxamide (CAS 681167-16-8)
- 4-{[(morpholin-4-yl)amino]methylidene}-3-phenyl-4,5-dihydro-1H-pyrazol-5-one (CAS 240799-40-0)
- 5-chloro-Barbituric acid (CAS 19645-77-3)
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- Ethyl 3-amino-3-(2-ethoxyphenyl)propanoate oxalate (CAS 502841-99-8)
- Semaglutide impurity 49 (CAS CATO-C4X-222649)
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