(2,4-Difluorophenyl)(thiazol-2-yl)methanone CAS 1443345-59-2
| CAS No. | 1443345-59-2 |
| Molecular Formula | C10H5F2NOS |
| Molecular Weight | 225.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies (2,4-Difluorophenyl)(thiazol-2-yl)methanone (CAS 1443345-59-2), a certified reference material (molecular formula C10H5F2NOS, MW 225.21 g/mol) for analytical method development and quality control.
(2,4-Difluorophenyl)(thiazol-2-yl)methanone (C10H5F2NOS) contains a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (2,4-Difluorophenyl)(thiazol-2-yl)methanone meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H5F2NOS |
| Molecular Weight | 225.21 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Difluorophenyl Standards
- (3,4-Difluorophenyl)(thiazol-2-yl)methanone (CAS 1086277-36-2)
- 2-(2,6-difluorophenyl)-1,3-thiazole-5-carbaldehyde (CAS 1235475-01-0)
- (2,3-Difluorophenyl)(thiazol-2-yl)methanone (CAS 1443306-86-2)
- (2,6-Difluorophenyl)(thiazol-2-yl)methanone (CAS 1443335-94-1)
- (2,5-Difluorophenyl)(thiazol-2-yl)methanone (CAS 1443345-51-4)
- (3,5-Difluorophenyl)(thiazol-2-yl)methanone (CAS 179113-65-6)
- 1-(2,4-Difluorophenyl)-N,N-dimethyl-1H-tetrazol-5-amine (CAS 338417-23-5)
- (2,5-Difluorophenyl)-4-piperidinyl-methanone (CAS 1016743-93-3)
Recommended Standards
- 4-(Trifluoromethyl)-<SC>L</SC>-phenylglycine (CAS 144789-75-3)
- 2-(3-(Trifluoromethyl)piperidin-1-yl)propanoic acid (CAS 1468921-15-4)
- 2-(4-(Trifluoromethyl)piperidin-1-yl)propanoic acid (CAS 1480279-71-7)
- 1-(3,3,3-Trifluoropropyl)piperidine-3-carboxylic acid (CAS 1410029-92-3)
- Naphthalen-2-yl benzenesulfonate (CAS 15161-07-6)
- ((2R,4r,6S)-1-Benzyl-2,6-dimethylpiperidin-4-yl)methanol (CAS 658705-14-7)
- 6-methoxy-1-indanone (CAS 13623-25-1)
- 5-Bromo-2-isopropoxybenzoic acid (CAS 62176-16-3)
- 2-(3-bromo-2-methyl-1H-indol-1-yl)acetic acid (CAS 954582-17-3)
- (R)-2-(4-bromophenyl)-2-hydroxyacetic acid (CAS 32189-34-7)
- N-ethyl-N-methylethanamine trifluoromethanesulfonate (CAS 945715-39-9)
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