4-(5-Bromo-2,3-difluorophenoxy)butanenitrile CAS 1443347-72-5
| CAS No. | 1443347-72-5 |
| Molecular Formula | C10H8BrF2NO |
| Molecular Weight | 276.08 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-(5-Bromo-2,3-difluorophenoxy)butanenitrile (C10H8BrF2NO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
4-(5-Bromo-2,3-difluorophenoxy)butanenitrile (CAS 1443347-72-5) is a high-purity analytical reference standard with the molecular formula C10H8BrF2NO and a molecular weight of 276.08 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-(5-Bromo-2,3-difluorophenoxy)butanenitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H8BrF2NO |
| Molecular Weight | 276.08 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
- 4-(4-Bromo-2,5-difluorophenoxy)butanenitrile (CAS 1443337-15-2)
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- 5-Bromo-2-(3,3-difluoroazetidin-1-yl)benzaldehyde (CAS 1707377-93-2)
- 2-Bromo-6-(3,3-difluoroazetidin-1-yl)benzaldehyde 1707377-96-5 (CAS 1707377-96-5)
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- Isopropyl 3-amino-3-(4-methoxyphenyl)propanoate (CAS 875159-56-1)
- (5-Hydroxybenzofuran-3-yl)(2-methoxyphenyl)methanone (CAS 1427020-40-3)
- Tirzepatide Impurity 18 (CAS CATO-C4X-324018)
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