Ethyl 3-(2,6-difluorophenoxy)propanoate CAS 1443347-75-8
| CAS No. | 1443347-75-8 |
| Molecular Formula | C11H12F2O3 |
| Molecular Weight | 230.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ethyl 3-(2,6-difluorophenoxy)propanoate.
CATO supplies Ethyl 3-(2,6-difluorophenoxy)propanoate (CAS 1443347-75-8), a certified reference material (molecular formula C11H12F2O3, MW 230.21 g/mol) for analytical method development and quality control.
The molecular framework of Ethyl 3-(2,6-difluorophenoxy)propanoate (C11H12F2O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures Ethyl 3-(2,6-difluorophenoxy)propanoate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H12F2O3 |
| Molecular Weight | 230.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
Related Ethyl Standards
- 2-(2,4-Difluorophenoxy)-3-methylbutanoic acid (CAS 1016734-04-5)
- Ethyl 3-(2,4-difluorophenoxy)propanoate (CAS 1099636-27-7)
- Ethyl 3-(3,4-difluorophenoxy)propanoate (CAS 1099636-88-0)
- 2-(2-(2,4-Difluorophenoxy)ethyl)-1,3-dioxolane (CAS 1225539-40-1)
- 2-(2-(3,4-Difluorophenoxy)ethyl)-1,3-dioxolane (CAS 1225539-47-8)
- Ethyl 3-(2,3-difluorophenoxy)propanoate (CAS 1341463-72-6)
- Ethyl 3-(2,5-difluorophenoxy)propanoate (CAS 1341783-35-4)
- Ethyl 3-(3,5-difluorophenoxy)propanoate (CAS 1344331-21-0)
Recommended Standards
- 2-(2-(3,5-Difluorophenoxy)ethyl)-1,3-dioxolane (CAS 1443345-85-4)
- 4-(2,2-Difluoropropoxy)-3-methylbenzoic acid (CAS 1476027-91-4)
- 2-(2-(2,6-Difluorophenoxy)ethyl)-1,3-dioxolane (CAS 1443345-72-9)
- 2,2-Difluoro-2-(2-isopropoxyphenyl)acetic acid (CAS 1514825-08-1)
- 2-Methyl-1,3-diazaspiro[4.4]Non-1-en-4-one (CAS 759442-73-4)
- 3-Bromo-N-(tert-butyl)-4-methoxybenzenesulfonamide (CAS 358665-60-8)
- 1-(2,2-Diethoxyethoxy)-4-(trifluoromethylsulfanyl)benzene (CAS 864685-34-7)
- (S)-tert-Butyl 2-(((S)-2-amino-N-ethylpropanamido)methyl)pyrrolidine-1-carboxylate (CAS 1401668-36-7)
- tert-Butyl (3-hydroxy-4-iodophenyl)carbamate (CAS 2353058-61-2)
- 2-[2-[[1-(4-Chlorophenyl)ethyl]amino]propanamido]thiophene-3-carboxamide (CAS 1214100-05-6)
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