1-(2-Chloroallyl)-4-fluoronaphthalene CAS 1443355-08-5
| CAS No. | 1443355-08-5 |
| Molecular Formula | C13H10ClF |
| Molecular Weight | 220.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 1-(2-Chloroallyl)-4-fluoronaphthalene (C13H10ClF) is characterized by fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
1-(2-Chloroallyl)-4-fluoronaphthalene (CAS 1443355-08-5) is a high-purity analytical reference standard with the molecular formula C13H10ClF and a molecular weight of 220.67 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-(2-Chloroallyl)-4-fluoronaphthalene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H10ClF |
| Molecular Weight | 220.67 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F/Cl-containing |
Related Chloroallyl Standards
- 1-(2-Chloroallyl)-2-(methylsulfonyl)-1H-imidazole (CAS 1384694-69-2)
- (E)-1-(3-Chloroallyl)quinazolin-4(1H)-one (CAS 28817-99-4)
- 1-(2-Chloroallyl)-4-(trifluoromethyl)benzene (CAS 951889-51-3)
- 4-(2-Chloroallyl)-3-(methylsulfonyl)-4h-1,2,4-triazole (CAS 1280945-92-7)
- 4-(2-Chloroallyl)thiomorpholine-3-carboxylic acid (CAS 1544016-77-4)
- 1-(2-Chloroallyl)-4-pentylbenzene (CAS 951890-87-2)
- 4-((2-Chloroallyl)oxy)-3-methoxybenzonitrile (CAS 1016800-80-8)
- (4-(2-Chloroallyl)phenyl)(ethyl)sulfane (CAS 951890-63-4)
Recommended Standards
- 5-Chloro-3-propoxythiophene-2-carboxylic acid (CAS 1392233-78-1)
- Methyl 3-(5-chlorothiophen-2-yl)-2-hydroxypropanoate (CAS 1510195-55-7)
- 4-Hydroxy-3,5-dimethylbenzenesulfonyl chloride (CAS 13432-82-1)
- 3-Methoxy-4-methylbenzenesulfonyl chloride (CAS 152708-83-3)
- Ethyl 3-hydroxy-7,8-dihydropyrido[4,3-c]pyridazine-6(5H)-carboxylate (CAS 39716-48-8)
- 1,4-Difluorophthalazine (CAS 57542-42-4)
- 5-Bromo-2-(perfluoropropyl)pyridine (CAS 1816282-96-8)
- Diethyl 2-((8-bromo-2-chloro-7-methoxyquinolin-3-yl)methylene)malonate (CAS 1031929-12-0)
- (S)-6-Ethylchroman-4-amine (CAS 1228566-51-5)
- Propyl 3-nitrobenzoate (CAS 59265-70-2)
- 3-(Benzyloxy)-4-methoxybenzonitrile (CAS 52805-37-5)
- 1-((6-Fluoroimidazo[1,2-a]pyridin-2-yl)methyl)piperidine-3-carboxylic acid (CAS 1713639-23-6)
- 4-amino-2-(trifluoromethyl)pyridine (CAS 147149-98-2)
- Semaglutide impurity 29 (CAS 110990-08-4)
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