2-((3,4-Difluorophenoxy)methyl)benzaldehyde CAS 1443355-36-9

Purity 97%+In StockPharmaceutical Standards
CAS No.1443355-36-9
Molecular FormulaC14H10F2O2
Molecular Weight248.22 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-((3,4-Difluorophenoxy)methyl)benzaldehyde CAS 1443355-36-9 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 248.22 g/mol gives 2-((3,4-Difluorophenoxy)methyl)benzaldehyde distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

2-((3,4-Difluorophenoxy)methyl)benzaldehyde (CAS 1443355-36-9) is a high-purity analytical reference standard with the molecular formula C14H10F2O2 and a molecular weight of 248.22 g/mol.

2-((3,4-Difluorophenoxy)methyl)benzaldehyde (C14H10F2O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-((3,4-Difluorophenoxy)methyl)benzaldehyde meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC14H10F2O2
Molecular Weight248.22 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1992
Halogen ContentF-containing

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