1-(3,4,5-Trimethoxybenzyl)piperidin-4-amine dihydrochloride CAS 1443424-30-3
| CAS No. | 1443424-30-3 |
| Molecular Formula | C15H24N2O3 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
1-(3,4,5-Trimethoxybenzyl)piperidin-4-amine dihydrochloride (CAS 1443424-30-3) is a high-purity analytical reference standard with the molecular formula C15H24N2O3HCl and a molecular weight of 316.83 g/mol.
1-(3,4,5-Trimethoxybenzyl)piperidin-4-amine dihydrochloride (C15H24N2O3HCl) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), 1-(3,4,5-Trimethoxybenzyl)piperidin-4-amine dihydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H24N2O3 2*HCl |
| Molecular Weight | 316.83 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Trimethoxybenzyl Standards
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- 5-Oxo-5-(4-(2,3,4-trimethoxybenzyl)piperazin-1-yl)pentanoic acid (CAS 1010936-56-7)
- N-(3,4,5-trimethoxybenzyl)cyclopentanamine hydrochloride (CAS 1052525-88-8)
- 1-(3,4,5-Trimethoxybenzyl)-1H-pyrazol-5-amine (CAS 1052547-81-5)
- 2,4,6-Trimethoxybenzyl bromide (CAS 1094663-93-0)
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- 1346598-93-3 3,4,5-Trimethoxybenzyl-13C3 Bromide (CAS 1346598-93-3)
- N-(2,4,5-trimethoxybenzyl)cyclopentanamine hydrobromide (CAS 1609395-84-7)
Recommended Standards
- (S)-4-(1-Amino-2,2,2-trifluoroethyl)benzonitrile hydrochloride (CAS 943731-61-1)
- (E)-[(3-Chloro-4-methoxyphenyl)methylidene][(4-chlorophenyl)methyl]amine (CAS 861207-76-3)
- (5-(1,3-Dioxolan-2-yl)thiophen-2-yl)(2-bromophenyl)methanone (CAS 898778-01-3)
- 2-Chloro-N-(3-(pyrrolidin-1-yl)propyl)benzenesulfonamide (CAS 321721-53-3)
- 3-(1-Hydroxyethylidene)-5-isobutylpyrrolidine-2,4-dione (CAS 237765-71-8)
- (7-Amino-2,2-difluorobenzo[d][1,3]dioxol-4-yl)dimethylphosphine oxide (CAS 2903924-00-3)
- tert-Butyl 1-methyl-6,7-dihydro-1H-pyrazolo[4,3-b]pyridine-4(5H)-carboxylate (CAS 1421311-98-9)
- 4-Nitro-2-phenyloxazole (CAS 151293-09-3)
- 7-Chloro-2-methyl-3,5-diphenylpyrazolo[1,5-a]pyrimidine (CAS 890623-84-4)
- Palmitoyl Tripeptide-5 TFA (CAS 623172-55-4（free base）)
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