Rogaratinib CAS 1443530-05-9
| CAS No. | 1443530-05-9 |
| Molecular Formula | C23H26N6O3S |
| Molecular Weight | 466.56 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 466.56 g/mol gives Rogaratinib distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Rogaratinib (CAS 1443530-05-9), molecular formula C23H26N6O3S and molecular weight 466.56 g/mol, is a CATO reference standard with documented purity and traceability.
Rogaratinib (C23H26N6O3S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H26N6O3S |
| Molecular Weight | 466.56 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Nitrogen Atoms | 6 |
| Sulfur Atoms | 1 |
Recommended Standards
- Apremilast Impurity 127 (CAS CATO-C4X-1009127)
- Androsterone Glucuronide (CAS 1852-43-3)
- N2-(Methylsulfonyl)-N2-trityl-L-glutamine (CAS 2230674-05-0)
- Epiandrosterone Glucuronide (CAS 4271-00-5)
- Methyl 2-cyclohexylthiazole-4-carboxylate (CAS 1547201-45-5)
- Methyl 2-(2-chloro-3,4-dimethoxyphenyl)acetate (CAS 6834-52-2)
- 2-(7-Methyl-1H-indazol-3-yl)ethanamine (CAS 1360884-36-1)
- 4-(Cyclopent-2-en-1-yl)morpholine (CAS 6284-13-5)
- 2-[(4-Aminophenyl)thio]-N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]acetamide (CAS 914204-21-0)
- 2-amino-2-(3,4,5-trifluorophenyl)ethan-1-ol hydrochloride (CAS 1423034-14-3)
- tert-Butyl 2-(hydroxymethyl)-1H-pyrrolo[3,2-c]pyridine-1-carboxylate (CAS 1330751-90-0)
- 3,5-Dichloro-2-hydrazinopyridine (CAS 104408-23-3)
- 4-Bromo-2-formylphenyl 4-methylbenzoate (CAS 431937-89-2)
- (Tyr?)-C-Peptide (human) (CAS 57327-90-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com