3-chloro-5-(chlorosulfonyl)-2,4-difluorobenzoic acid CAS 1443980-60-6

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-chloro-5-(chlorosulfonyl)-2,4-difluorobenzoic acid.

3-chloro-5-(chlorosulfonyl)-2,4-difluorobenzoic acid (CAS 1443980-60-6), molecular formula C7H2Cl2F2O4S and molecular weight 291.06 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system, 3-chloro-5-(chlorosulfonyl)-2,4-difluorobenzoic acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 291.06 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 3-chloro-5-(chlorosulfonyl)-2,4-difluorobenzoic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

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