2,2,2-trifluoro-1-[2-(trifluoromethyl)phenyl]ethan-1-amine hydrochloride CAS 1443981-34-7
| CAS No. | 1443981-34-7 |
| Molecular Formula | C9H7F6N |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2,2,2-trifluoro-1-[2-(trifluoromethyl)phenyl]ethan-1-amine hydrochloride (C9H7F6NHCl) is characterized by a nitrile group, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
2,2,2-trifluoro-1-[2-(trifluoromethyl)phenyl]ethan-1-amine hydrochloride (CAS 1443981-34-7) is a high-purity analytical reference standard with the molecular formula C9H7F6NHCl and a molecular weight of 279.61 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H7F6N HCl |
| Molecular Weight | 279.61 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related trifluoro Standards
- Ethyl 6,7,8-trifluoro-1-(N-methylformamido)-4-oxo-1,4-dihydroquinoline-3-carboxylate (CAS 100276-65-1)
- ethyl 6,7,8-trifluoro-1-(methylamino)-4-oxo-1,4-dihydroquinoline-3-carboxylate (CAS 100276-66-2)
- 1,1,1-Trifluoro-3-(1-methyl-1h-imidazol-2-yl)propan-2-ol (CAS 100282-72-2)
- Ethyl 5,5,5-trifluoro-2-oxopentanoate (CAS 1003322-53-9)
- 2,4,5-Trifluoro-3-methoxy-6-methylbenzonitrile (CAS 1003708-50-6)
- 2,2,2-Trifluoro-1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethan-1-one (CAS 1004294-77-2)
- 4,4,4-Trifluoro-1-(3-nitrophenyl)-3-(trifluoromethyl)but-2-en-1-ol (CAS 100482-54-0)
- 4,4,4-Trifluoro-1-(thiophen-2-yl)-3-(trifluoromethyl)but-2-en-1-ol (CAS 100482-55-1)
Recommended Standards
- 3-FLuoro-5-hydroxybenzohydrazide (CAS 1394982-23-0)
- 2-((4-Chlorobenzyl)(isopropyl)amino)ethanol (CAS 1247188-42-6)
- 3,4-Dichloro-N'-(4,6-dimethyl-3-(methylsulfonyl)pyridin-2-yl)-N'-methylbenzohydrazide (CAS 341967-40-6)
- 2-((7H-purin-6-yl)thio)acetamide (CAS 74537-19-2)
- 3-Azido Neomycin BDISCONTINUED. Please see A854595 (CAS 1448168-05-5)
- 1365962-06-6 2-Chloro-N-(3-cyano-6-methyl-4,5,6,7-tetrahydro-1-benzothien-2-yl)-2-phenylacetamide MFCD22056619 (CAS 1365962-06-6)
- 4,4,4-trifluoro-2-methylbutane-1-sulfonyl chloride (CAS 1784373-64-3)
- N-(Furan-2-ylmethyl)-2-((1-(3-hydroxypropyl)-2-oxo-1,2,5,6,7,8-hexahydroquinazolin-4-yl)thio)acetamide (CAS 899974-01-7)
- methyl 3-formyl-1h-indole-7-carboxylate (CAS 312973-24-3)
- Semaglutide Impurity 5 (CAS 23406-82-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com