rac-GDC-0927, >98% (HPLC) CAS 1443983-36-5
| CAS No. | 1443983-36-5 |
| Molecular Formula | C28H28FNO4 |
| Molecular Weight | 461.52 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including rac-GDC-0927, >98% (HPLC).
CATO supplies rac-GDC-0927, >98% (HPLC) (CAS 1443983-36-5), a certified reference material (molecular formula C28H28FNO4, MW 461.52 g/mol) for analytical method development and quality control.
The molecular framework of rac-GDC-0927, >98% (HPLC) (C28H28FNO4) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), rac-GDC-0927, >98% (HPLC) meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C28H28FNO4 |
| Molecular Weight | 461.52 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- 2-(4-(2-(1-Isopropyl-3-methyl-1H-1,2,4-triazol-5-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepin-9-yl)-1H-pyrazol-1-yl)-2-methylpropanoic acid (CAS 1282513-03-4)
- N-(3-((2-Amino-6-methylpyrimidin-4-yl)amino)phenyl)-3-(quinolin-4-ylamino)benzamide (CAS 1535187-91-7)
- SGI-1027 (CAS 1020149-73-8)
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- 1-[3-Nitro-4-(1H-pyrazol-1-yl)phenyl]ethanone (CAS 1152964-28-7)
- 2-(Dimethylamino)-9-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one (CAS 88127-22-4)
- n-Isobutyl-2-(4-methyl-2-oxothiazol-3(2h)-yl)acetamide (CAS 923106-57-4)
- 3-Ethynylbicyclo[4.2.0]octa-1,3,5-triene (CAS 144597-22-8)
- 2-Chloro-N-(4-methoxybenzyl)nicotinamide (CAS 125038-59-7)
- 5-Bromo-N-cyclobutyl-2-methylbenzamide (CAS 1469032-10-7)
- 2,4,6-Triethyl-1,3,5-trioxane (CAS 2396-42-1)
- N-((tetrahydrofuran-2-yl)methyl)benzo[d]thiazole-6-sulfonamide (CAS 1427460-47-6)
- 2-allyloxy-2-methyl-propanoic acid (CAS 17859-93-7)
- Biotinyl-Glucagon (1-29) (human, rat, porcine) trifluoroacetate salt (CAS 1802086-28-7)
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