(3-(2,2,2-Trifluoro-1-hydroxyethyl)phenyl)boronic acid CAS 1443986-87-5
| CAS No. | 1443986-87-5 |
| Molecular Formula | C8H8BF3O3 |
| Molecular Weight | 219.95 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, (3-(2,2,2-Trifluoro-1-hydroxyethyl)phenyl)boronic acid is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 219.95 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies (3-(2,2,2-Trifluoro-1-hydroxyethyl)phenyl)boronic acid (CAS 1443986-87-5), a certified reference material (molecular formula C8H8BF3O3, MW 219.95 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H8BF3O3 |
| Molecular Weight | 219.95 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
Related Trifluoro Standards
- (4-(2,2,2-Trifluoro-1-hydroxyethyl)phenyl)boronic acid (CAS 1346526-55-3)
- 4,4,4-Trifluoro-1-(1-methyl-1h-pyrazol-4-yl)butane-1,3-dione (CAS 1005592-50-6)
- 4,4,4-Trifluoro-1-(1-methyl-1h-pyrazol-3-yl)butane-1,3-dione (CAS 1006319-27-2)
- Ethyl 2,3,5-trifluoro-4-hydroxybenzoate (CAS 1214351-42-4)
- 2,2,2-Trifluoro-1-(3-nitrophenyl)ethan-1-amine (CAS 1248504-66-6)
- 2,2,2-Trifluoro-1-(4-nitrophenyl)ethanamine (CAS 1270543-98-0)
- Ethyl 2,4,5-trifluoro-3-hydroxybenzoate (CAS 128426-84-6)
- (S)-4-(2,2,2-Trifluoro-1-hydroxyethyl)benzoic acid (CAS 130534-97-3)
Recommended Standards
- (5-Methoxy-2-(trifluoromethyl)phenyl)boronic acid (CAS 1437787-72-8)
- 4-Methoxy-3-(trifluoromethyl)phenylboronic Acid (CAS 149507-36-8)
- (3-Methyl-5-(trifluoromethoxy)phenyl)boronic acid (CAS 1417301-61-1)
- (2-(Hydroxymethyl)-4-(trifluoromethyl)phenyl)boronic acid (CAS 1629148-48-6)
- Ethyl 3-[(diphenylmethyl)amino]propanoate (CAS 289637-69-0)
- (2-(M-tolyl)cyclopropyl)methanamine (CAS 1226323-76-7)
- 1-ethyl-2-(isothiocyanatomethyl)pyrrolidine (CAS 51218-09-8)
- 2-(4-Chlorophenyl)-2-(1-pyrrolidinyl)ethylamine (CAS 915923-59-0)
- 1-Methyl-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine (CAS 87673-88-9)
- 7-(1,1-Dimethylethyl)-3-(2,6-dimethylphenyl)-2,3,5,6,7,8-hexahydro-2-thioxo[1]benzothieno[2,3-d]pyrimidin-4(1H)-one (CAS 744227-08-5)
- Valsartan Impurity 144 (CAS 149690-12-0)
- 2-azatricyclo[7.3.0.0^{3,7}]dodeca-1,3(7),8-triene (CAS 34421-99-3)
- (S)-Ethyl 2-((tert-butoxycarbonyl)amino)-3-(4-iodophenyl)propanoate (CAS 943148-40-1)
- Insulin Degludec Impurity 27 (CAS CATO-C4X-215727)
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