4-Chloro-5,6-difluoro-2-methylquinazoline CAS 1444348-81-5
| CAS No. | 1444348-81-5 |
| Molecular Formula | C9H5ClF2N2 |
| Molecular Weight | 214.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 214.60 g/mol gives 4-Chloro-5,6-difluoro-2-methylquinazoline distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
4-Chloro-5,6-difluoro-2-methylquinazoline (CAS 1444348-81-5), molecular formula C9H5ClF2N2 and molecular weight 214.60 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 4-Chloro-5,6-difluoro-2-methylquinazoline (C9H5ClF2N2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 214.60 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 4-Chloro-5,6-difluoro-2-methylquinazoline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H5ClF2N2 |
| Molecular Weight | 214.60 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 4-chloro-2-(difluoromethyl)quinazoline (CAS 1039312-08-7)
- 3-Chloro-6-((trifluoromethyl)thio)pyridazine (CAS 1206523-89-8)
- 2-Chloro-6-trifluoromethylsulfanylpyrazine (CAS 1206524-06-2)
- 2-Chloro-5-((trifluoromethyl)thio)pyrazine (CAS 1206524-19-7)
- 4-Chloro-2-(methoxycarbonyl)benzoic acid (CAS 1310531-95-3)
- 4-Chloro-6-(trifluoromethyl)pyrimidine-2-thiol (CAS 1379310-59-4)
- 6-Chloro-2-formyl-3-hydroxy-benzoic acid methyl ester (CAS 1427373-63-4)
- 2-(4-Chloro-2-formylphenoxy)acetic acid (CAS 14440-47-2)
Recommended Standards
- 4-Chloro-6,8-difluoro-2-methylquinazoline (CAS 1444353-33-6)
- Methyl 3-chloro-4,5-methylenedioxybenzoate (CAS 1490946-47-8)
- 2-(7-Chloro-1,3-dioxaindan-5-yl)acetic acid (CAS 1506033-20-0)
- 3-Chloro-5-(methoxycarbonyl)benzoic Acid (CAS 153203-57-7)
- 2-(6-(Trifluoromethyl)-1H-indol-3-yl)acetonitrile (CAS 408354-37-0)
- Methyl (5-(chlorosulfonyl)naphthalen-1-yl)carbamate (CAS 824413-50-5)
- 1-Boc-4-(Indol-5-yl)piperidine (CAS 1049677-53-3)
- 4-Methyl-2-(p-tolyl)-1H-imidazole-5-carboxylic acid (CAS 1153735-07-9)
- 4-(5-(4-Methoxyphenyl)-1,3,4-oxadiazol-2-yl)benzene-1,2-diamine (CAS 1137671-57-8)
- 3-Chloro-6-(3-(trifluoromethyl)-3H-diazirin-3-yl)isoquinoline (CAS 2231675-97-9)
- 5-Bromo-2-methoxy-4-methylphenol (CAS 83387-13-7)
- 3-amino-2-[(2-bromophenyl)methyl]propan-1-ol hydrochloride (CAS 1795508-54-1)
- 2-(Piperidin-1-ylmethyl)benzaldehyde (CAS 61200-70-2)
- KALA Amphipathic Peptide (CAS 187987-64-0)
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