3-(tert-Butyl-dimethyl-silanyloxy)-2S,3-dimethyl-butan-1-ol CAS 144436-47-5

Purity 97%+In StockPharmaceutical Standards
CAS No.144436-47-5
Molecular FormulaC12H28O2Si
Molecular Weight232.44 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3-(tert-Butyl-dimethyl-silanyloxy)-2S,3-dimethyl-butan-1-ol CAS 144436-47-5 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

3-(tert-Butyl-dimethyl-silanyloxy)-2S,3-dimethyl-butan-1-ol (CAS 144436-47-5) is a high-purity analytical reference standard with the molecular formula C12H28O2Si and a molecular weight of 232.44 g/mol.

The molecular framework of 3-(tert-Butyl-dimethyl-silanyloxy)-2S,3-dimethyl-butan-1-ol (C12H28O2Si) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

As a certified reference material (CRM), 3-(tert-Butyl-dimethyl-silanyloxy)-2S,3-dimethyl-butan-1-ol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC12H28O2Si
Molecular Weight232.44 g/mol
Purity97%+
StorageStore at room temperature
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityStable under recommended storage conditions
Degree of Unsaturation (DBE)-1.0
CAS Registry Year (est.)1998

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