2,4-Dimethoxypyrimidine-5-carbonitrile CAS 14445-57-9
| CAS No. | 14445-57-9 |
| Molecular Formula | C7H7N3O2 |
| Molecular Weight | 165.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 165.15 g/mol gives 2,4-Dimethoxypyrimidine-5-carbonitrile distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2,4-Dimethoxypyrimidine-5-carbonitrile (CAS 14445-57-9) is a high-purity analytical reference standard with the molecular formula C7H7N3O2 and a molecular weight of 165.15 g/mol.
The molecular framework of 2,4-Dimethoxypyrimidine-5-carbonitrile (C7H7N3O2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2,4-Dimethoxypyrimidine-5-carbonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H7N3O2 |
| Molecular Weight | 165.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
| Nitrogen Atoms | 3 |
Related Dimethoxypyrimidine Standards
- 2,6-Dimethoxypyrimidine-4-carbonitrile (CAS 100868-70-0)
- 4,6-Dimethoxypyrimidine-2-carbaldehyde (CAS 125966-89-4)
- 4,6-Dimethoxypyrimidine-5-carbaldehyde (CAS 4558-59-2)
- 4,6-Dimethoxypyrimidine-2-methanol (CAS 125966-88-3)
- 4,6-dimethoxypyrimidine-2-carbonitrile (CAS 139539-63-2)
- 4,6-Dimethoxypyrimidine-2-thiol (CAS 57235-35-5)
- 2,6-Dimethoxypyrimidine-4-boronic Acid (CAS 852362-23-3)
- 2,4-Dimethoxypyrimidine-5-carboxylic acid (CAS 110821-07-3)
Recommended Standards
- 3-(1-methyl-1H-imidazol-2-yl)-1,2,4-oxadiazol-5-amine (CAS 1423032-33-0)
- 2-(4-Nitrophenyl)acetaldehyde (CAS 1460-05-5)
- 5-(1-methyl-1H-imidazol-2-yl)-1,3,4-oxadiazol-2-amine (CAS 1421601-89-9)
- 5-Acetylpyrazine-2-carboxamide (CAS 147425-79-4)
- ethyl 2-bromo-3,3,3-trideuterio-propanoate (CAS 1398066-14-2)
- Tert-butyl (S)-5-amino-2-azaspiro[3.3]Heptane-2-carboxylate (CAS 2381334-14-9)
- 2-(Chloromethyl)-4-(difluoromethyl)pyridine-3-sulfonamide (CAS 1805305-04-7)
- 3,4-Difluoro-5-nitrophenacyl bromide (CAS 1803809-42-8)
- Ethyl 5-((1-(pyrimidin-2-yl)piperidine-4-carboxamido)methyl)-4,5-dihydroisoxazole-3-carboxylate (CAS 306978-06-3)
- 1,1-Dicarbethoxycyclopropane (CAS 1559-02-0)
- 5-Methyl-2-(methylthio)-[1,2,4]triazolo[1,5-a]pyrimidine (CAS 56347-12-7)
- Holmium carbonate hydrate, 99.90% (CAS 38245-34-0)
- Methyl 3-(Cyclopropylamino)propanoate (CAS 77497-84-8)
- Semaglutide Impurity 82 (CAS CATO-C4X-222682)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com