14446-73-2 3-amino-8-methyl-4H-pyrido[1,2-a]pyrimidin-4-one CAS 14446-73-2

Purity 97%+In StockPharmaceutical Standards
CAS No.14446-73-2
Molecular FormulaC11H21N
Molecular Weight167.29 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

14446-73-2
3-amino-8-methyl-4H-pyrido[1,2-a]pyrimidin-4-one CAS 14446-73-2 chemical structure

Description

14446-73-2 3-amino-8-methyl-4H-pyrido[1,2-a]pyrimidin-4-one (CAS 14446-73-2), molecular formula C11H21N and molecular weight 167.29 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 14446-73-2 3-amino-8-methyl-4H-pyrido[1,2-a]pyrimidin-4-one (C11H21N) is characterized by a nitrile group. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC11H21N
Molecular Weight167.29 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)2.0
CAS Registry Year (est.)1961
Nitrogen Atoms1

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