1-Boc-2-methyl-4-oxo-D-proline CAS 144527-34-4
| CAS No. | 144527-34-4 |
| Molecular Formula | C11H17NO5 |
| Molecular Weight | 243.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-Boc-2-methyl-4-oxo-D-proline (CAS 144527-34-4) is a high-purity analytical reference standard with the molecular formula C11H17NO5 and a molecular weight of 243.26 g/mol.
1-Boc-2-methyl-4-oxo-D-proline (C11H17NO5) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H17NO5 |
| Molecular Weight | 243.26 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Nitrogen Atoms | 1 |
Recommended Standards
- N-(5-(4-Methoxyphenyl)pyrazin-2-yl)acetamide (CAS 144465-03-2)
- Ethyl 2-(5-methylpyridin-2-yl)pyrimidine-5-carboxylate (CAS 1447607-28-4)
- Benzyl 2,6-dihydropyrrolo[3,4-c]pyrazole-5(4H)-carboxylate (CAS 1440526-63-5)
- (4-(Methoxymethoxy)phenyl)(pyridin-3-yl)methanone (CAS 144824-63-5)
- 1-(4-Methoxy-2-nitrophenyl)-1H-imidazole (CAS 25372-06-9)
- 3-(Perfluoroethyl)-1H-pyrazole (CAS 184782-98-7)
- 1-[1-(2,2,2-trifluoroethyl)piperidin-4-yl]ethan-1-one hydrochloride (CAS 1803596-34-0)
- 2-Acetyl-7-bromofluorene (CAS 34172-50-4)
- 2-(1-azidoethyl)-3-chloro-pyrazine (CAS 440672-65-1)
- 3-((5-Methyl-5H-pyrrolo[3,2-d]pyrimidin-4-yl)oxy)benzoic acid (CAS 919278-71-0)
- 1-(4-Isopropylphenyl)hexan-1-one (CAS 42144-18-3)
- Oxacillin Impurity 58 (CAS CATO-C4X-232158)
- (R)-tert-Butyl (2-(hydroxymethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-6-yl)carbamate (CAS 2648219-47-8)
- Semaglutide impurity 237 (CAS CATO-C4X-2226237)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com