6-Chlorospiro[indoline-3,4'-piperidin]-2-one hydrochloride CAS 1445603-38-2

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-Chlorospiro[indoline-3,4'-piperidin]-2-one hydrochloride.

6-Chlorospiro[indoline-3,4'-piperidin]-2-one hydrochloride (CAS 1445603-38-2), molecular formula C12H13ClN2OHCl and molecular weight 273.16 g/mol, is a CATO reference standard with documented purity and traceability.

6-Chlorospiro[indoline-3,4'-piperidin]-2-one hydrochloride (C12H13ClN2OHCl) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 6-Chlorospiro[indoline-3,4'-piperidin]-2-one hydrochloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

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