N-[4-(4-Acetylpiperazin-1-yl)-2-fluorobenzyl]-N-cyclobutyl-C-phenyl-methanesulfonamide CAS 1445901-80-3
| CAS No. | 1445901-80-3 |
| Molecular Formula | C24H30FN3O3S |
| Molecular Weight | 459.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies N-[4-(4-Acetylpiperazin-1-yl)-2-fluorobenzyl]-N-cyclobutyl-C-phenyl-methanesulfonamide (CAS 1445901-80-3), a certified reference material (molecular formula C24H30FN3O3S, MW 459.58 g/mol) for analytical method development and quality control.
N-[4-(4-Acetylpiperazin-1-yl)-2-fluorobenzyl]-N-cyclobutyl-C-phenyl-methanesulfonamide (C24H30FN3O3S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), N-[4-(4-Acetylpiperazin-1-yl)-2-fluorobenzyl]-N-cyclobutyl-C-phenyl-methanesulfonamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C24H30FN3O3S |
| Molecular Weight | 459.58 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related N Standards
- (E)-1-(4-Acetylpiperazin-1-yl)-3-(4-((2-isopropylphenyl)thio)-3-nitrophenyl)prop-2-en-1-one (CAS 280749-17-9)
- N-(5-(4-Acetylpiperazin-1-yl)pyridin-2-yl)-2-(2'-fluoro-3-methyl-[2,4'-bipyridin]-5-yl)acetamide (CAS 1243245-18-2)
- N-[4-(4-Acetylpiperazin-1-yl)-2-fluorobenzyl]-3,5-dichloro-N-cyclobutyl-benzenesulfonamide (CAS 1445901-81-4)
- 1-(4-(3-(4-Acetylpiperazin-1-yl)-3-oxopropyl)thiazol-2-yl)-3-phenylurea (CAS 1040648-55-2)
- [[2-(4-Acetylpiperazin-1-yl)-2-oxoethyl]-(4-methoxyphenyl)amino]acetic acid (CAS 1142205-48-8)
- 4-(4-Acetylpiperazin-1-yl)phenyl 2-(thiophen-2-yl)acetate (CAS 862886-11-1)
- 8-(4-Acetylpiperazin-1-yl)-3-methyl-7-propyl-3,7-dihydro-1H-purine-2,6-dione (CAS 304878-39-5)
- 3-[(4-acetylpiperazin-1-yl)sulfonyl]-4-fluorobenzoic acid (CAS 1053994-99-2)
Recommended Standards
- (2S,4R)-tert-Butyl 4-hydroxy-2-((trityloxy)methyl)pyrrolidine-1-carboxylate (CAS 1315590-89-6)
- GNE-3500, >98% (HPLC) (CAS 1537859-24-7)
- N-(naphthalen-2-yl)-9,9-diphenyl-9H-fluoren-2-amine (CAS 1198395-23-1)
- N,N-Di-(tert-butyloxy)-3-[[[3-(ethylamino)propyl]amino]methyl]-4-quinolinol (CAS 1797132-25-2)
- 4-(2-Fluoro-4-nitrophenyl)-1-methyl-1,4,5,6-tetrahydro-1,2,4-triazine (CAS 1334167-66-6)
- n-(1-Cyanopropan-2-yl)-3-ethyl-N-methylthiophene-2-carboxamide (CAS 1333725-11-3)
- 5-Chloro-2-fluoro-4-methylbenzoic Acid (CAS 1263274-67-4)
- Ezetimibe Impurity 111 (CAS CATO-C4X-1098111)
- (R)-2-((tert-Butoxycarbonyl)amino)-4-(4-(trifluoromethyl)phenyl)butanoic acid (CAS 1082750-53-5)
- Di-tert-butyl propane-1,1-diyldicarbamate (CAS 1496636-53-3)
- N-(3-Amino-4-methoxyphenyl)propanamide (CAS 58050-03-6)
- 2-Bromo-4-methoxyphenylboronic acid (CAS 1879166-84-3)
- N-Allyloxycarbonyl 8-Ethoxy Moxifloxacin Ethyl Ester (CAS 1329840-03-0)
- Semaglutide Impurity 184 (CAS CATO-C4X-2226184)
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