tert-Butyl (3aR,6aR)-2-(iodomethyl)hexahydro-5H-furo[2,3-c]pyrrole-5-carboxylate CAS 1445949-63-2
| CAS No. | 1445949-63-2 |
| Molecular Formula | C12H20INO3 |
| Molecular Weight | 353.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including tert-Butyl (3aR,6aR)-2-(iodomethyl)hexahydro-5H-furo[2,3-c]pyrrole-5-carboxylate.
tert-Butyl (3aR,6aR)-2-(iodomethyl)hexahydro-5H-furo[2,3-c]pyrrole-5-carboxylate (CAS 1445949-63-2) is a high-purity analytical reference standard with the molecular formula C12H20INO3 and a molecular weight of 353.20 g/mol.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, iodine substitution, tert-Butyl (3aR,6aR)-2-(iodomethyl)hexahydro-5H-furo[2,3-c]pyrrole-5-carboxylate is typically white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 353.20 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H20INO3 |
| Molecular Weight | 353.20 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- P,P-bis(4-(trifluoromethyl)phenyl)phosphinic amide (CAS 1333316-91-8)
- Racemic-(2S,3aS,6aS)-tert-butyl 2-(iodomethyl)tetrahydro-2H-furo[2,3-c]pyrrole-5(3H)-carboxylate (CAS 1445951-05-2)
- N-(4-Bromophenyl)-2-(6-oxo-5,6-dihydrothiazolo[3,2-b][1,2,4]triazol-5-yl)acetamide (CAS 501112-06-7)
- tert-Butyl (4,5-dichloro-9H-pyrimido[4,5-b]indol-2-yl)carbamate (CAS 1447606-59-8)
- 1-(2-Amino-4-methyloxazol-5-yl)ethanone (CAS 191399-17-4)
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- 2-Bromo-4-fluoro-N-(3-fluorobenzyl)aniline (CAS 1038978-91-4)
- 8-Bromo-6-methylimidazo[1,2-a]pyridine-2-carboxylic acid (CAS 1203571-75-8)
- N-(3-carbamimidamidophenyl)acetamide (CAS 150784-53-5)
- Semaglutide impurity 196 (CAS CATO-C4X-2226196)
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