2,2,2-Trifluoro-1-(2-fluoro-6-hydroxyphenyl)ethan-1-one CAS 1445995-75-4

Purity 97%+In StockPharmaceutical Standards
CAS No.1445995-75-4
Molecular FormulaC8H4F4O2
Molecular Weight208.11 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2,2,2-Trifluoro-1-(2-fluoro-6-hydroxyphenyl)ethan-1-one CAS 1445995-75-4 chemical structure

Description

2,2,2-Trifluoro-1-(2-fluoro-6-hydroxyphenyl)ethan-1-one (CAS 1445995-75-4) is a high-purity analytical reference standard with the molecular formula C8H4F4O2 and a molecular weight of 208.11 g/mol.

2,2,2-Trifluoro-1-(2-fluoro-6-hydroxyphenyl)ethan-1-one (C8H4F4O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 2,2,2-Trifluoro-1-(2-fluoro-6-hydroxyphenyl)ethan-1-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC8H4F4O2
Molecular Weight208.11 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at room temperature, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1992
Halogen ContentF-containing

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