4-Bromo-3-(trifluoromethyl)benzene-1,2-diamine CAS 1445995-83-4
| CAS No. | 1445995-83-4 |
| Molecular Formula | C7H6BrF3N2 |
| Molecular Weight | 255.04 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 4-Bromo-3-(trifluoromethyl)benzene-1,2-diamine (C7H6BrF3N2) is characterized by a nitrile group, fluorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies 4-Bromo-3-(trifluoromethyl)benzene-1,2-diamine (CAS 1445995-83-4), a certified reference material (molecular formula C7H6BrF3N2, MW 255.04 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-Bromo-3-(trifluoromethyl)benzene-1,2-diamine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H6BrF3N2 |
| Molecular Weight | 255.04 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 2 |
Related Bromo Standards
- (3-Bromo-5-(trifluoromethyl)phenyl)hydrazine (CAS 1001462-89-0)
- 4-Bromo-5-cyclopropyl-3-(trifluoromethyl)-1H-pyrazole (CAS 1057659-72-9)
- 3-Bromo-5-(trifluoromethyl)benzene-1,2-diamine (CAS 113170-72-2)
- (4-Bromo-6-(trifluoromethyl)pyridin-2-yl)methanamine (CAS 1196153-70-4)
- 3-Bromo-N-methyl-5-(trifluoromethyl)pyridin-2-amine (CAS 1256811-19-4)
- 5-Bromo-N-methyl-3-(trifluoromethyl)pyridin-2-amine (CAS 1257431-68-7)
- (5-Bromo-2-(trifluoromethyl)pyridin-4-yl)methanamine (CAS 1372096-32-6)
- 1-(3-Bromo-4-(trifluoromethyl)phenyl)hydrazine (CAS 1388029-40-0)
Recommended Standards
- (5-Bromo-3-(trifluoromethyl)pyridin-2-yl)methanamine (CAS 1416768-36-9)
- 5-Bromo-3-(trifluoromethyl)benzene-1,2-diamine (CAS 157026-19-2)
- 1,2-Diamino-4-bromo-5-(trifluoromethyl)benzene (CAS 157590-60-8)
- 2-(Aminomethyl)-3-bromo-4-(difluoromethyl)-6-fluoropyridine (CAS 1804635-92-4)
- (2-Bromophenyl)(quinolin-3-yl)methanone (CAS 350698-78-1)
- 6-Oxo-4-(trifluoromethyl)-1,6-dihydro-[2,3'-bipyridine]-5-carbonitrile (CAS 308088-11-1)
- tert-butyl N-[(tert-butoxy)carbonyl]-N-{3-iodo-1H-pyrazolo[3,4-d]pyrimidin-4-yl}carbamate (CAS 1513882-52-4)
- 7-Bromo-2-(methylthio)-1H-benzo[d]imidazole-5-carboxylic acid (CAS 1378255-04-9)
- (S)-3-((1R,3R,5S)-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-aza-bicyclo[3.2.1]octan-8-yl)-1-phenylpropan-1-amine (CAS 376348-71-9)
- 3-Methoxypyridin-4(1H)-one (CAS 50700-60-2)
- Ethyl 2-bromo-4-(bromomethyl)-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-imidazole-5-carboxylate (CAS 2866420-79-1)
- 2-Chloro-N-(1-ethyl-3,5-dimethyl-1H-pyrazol-4-yl)acetamide hydrochloride (CAS 1147231-06-8)
- 6-Bromo-8-methoxyimidazo[1,2-a]pyrazine-3-carbonitrile (CAS 2791314-62-8)
- Semaglutide impurity 215 (CAS CATO-C4X-2226215)
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