(2R,5S)-7-[(2-Methylpropan-2-yl)oxycarbonyl]-1-oxa-7-azaspiro[4.4]nonane-2-carboxylic acid CAS 1446012-43-6
| CAS No. | 1446012-43-6 |
| Molecular Formula | C13H21NO5 |
| Molecular Weight | 271.31 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
(2R,5S)-7-[(2-Methylpropan-2-yl)oxycarbonyl]-1-oxa-7-azaspiro[4.4]nonane-2-carboxylic acid (CAS 1446012-43-6), molecular formula C13H21NO5 and molecular weight 271.31 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (2R,5S)-7-[(2-Methylpropan-2-yl)oxycarbonyl]-1-oxa-7-azaspiro[4.4]nonane-2-carboxylic acid (C13H21NO5) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures (2R,5S)-7-[(2-Methylpropan-2-yl)oxycarbonyl]-1-oxa-7-azaspiro[4.4]nonane-2-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H21NO5 |
| Molecular Weight | 271.31 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Nitrogen Atoms | 1 |
Recommended Standards
- Cis-5-(Tert-Butoxycarbonyl)Hexahydro-1H-Furo[3,4-C]Pyrrol-3A-Yl)Acetic Acid (CAS 1445951-70-1)
- Methyl 6-(4-ethoxyphenyl)-2-methylnicotinate (CAS 1447960-36-2)
- Racemic-2-((2R,3aS,6aS)-5-(tert-butoxycarbonyl)hexahydro-2H-furo[2,3-c]pyrrol-2-yl)acetic acid (CAS 1445951-51-8)
- Ethyl 3-(cyclopropyl(3-ethoxy-3-oxopropyl)amino)-3-oxopropanoate (CAS 1453423-54-5)
- n-(4-(Aminomethyl)phenyl)-N-methylethanesulfonamide (CAS 1018281-12-3)
- trans-2-[1-(2-fluorophenyl)-1H-pyrazol-4-yl]oxolane-3-carboxylic acid (CAS 1820580-26-4)
- (2-Methylpyrrolidin-2-yl)methanamine (CAS 71318-23-5)
- 2-(4-Methyl-1H-pyrazol-1-yl)propan-1-ol (CAS 1177277-83-6)
- 1-(3-Chloro-phenyl)-3-mercapto-5,6,7,8-tetrahydro-isoquinoline-4-carbonitrile (CAS 380443-05-0)
- Propargyl-PEG9-bromide (CAS 2055042-83-4)
- tert-butyl N-(2-amino-2-cyclopentylethyl)carbamate (CAS 1270369-63-5)
- 5-Cyclopropoxy-6-methoxy-N,N-dimethylpicolinamide (CAS 1243407-82-0)
- (4AS,8S,8aS)-2-acetamido-8a-acetyl-6-methyl-4-oxo-1,4,4a,5,8,8a-hexahydroquinazolin-8-yl acetate (CAS 86970-99-2)
- Semaglutide impurity 271 (CAS CATO-C4X-2226271)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com