4-Chloro-2-methylphenyl trifluoromethanesulfonate CAS 1446016-75-6
| CAS No. | 1446016-75-6 |
| Molecular Formula | C8H6ClF3O3S |
| Molecular Weight | 274.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies 4-Chloro-2-methylphenyl trifluoromethanesulfonate (CAS 1446016-75-6), a certified reference material (molecular formula C8H6ClF3O3S, MW 274.64 g/mol) for analytical method development and quality control.
Structurally, 4-Chloro-2-methylphenyl trifluoromethanesulfonate (C8H6ClF3O3S) contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 274.64 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C8H6ClF3O3S |
| Molecular Weight | 274.64 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F/Cl-containing |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 4'-Chloro-4-fluoro-3-(trifluoromethyl)-1,1'-biphenyl (CAS 1032506-90-3)
- 4-Chloro-4'-fluoro-2-(trifluoromethyl)-1,1'-biphenyl (CAS 1214334-97-0)
- Methyl 5-chloro-3-(2,2,2-trifluoroethoxy)thiophene-2-carboxylate (CAS 1707727-79-4)
- 2-Chloro-4-(4-(trifluoromethyl)phenoxy)pyrimidine (CAS 1208087-07-3)
- 2-Chloro-N-(4-(trifluoromethyl)pyridin-2-yl)pyrimidin-4-amine (CAS 1361197-71-8)
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Recommended Standards
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- Ethyl 2-Cyano-2-methyl-3-phenylpropanoate (CAS 104876-35-9)
- 1-Benzyl 2-methyl (2R)-5-oxopyrrolidine-1,2-dicarboxylate (CAS 690211-34-8)
- 16β-Hydroxy Norgestrel (CAS 40915-03-5)
- 1-(2-Amino-2-cyclopropylethyl)-3-propylurea (CAS 1340253-16-8)
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- 2-(3,4-Difluorophenyl)propan-1-ol (CAS 1465087-96-0)
- 4-chloro-3-methyl-1,2-oxazole-5-sulfonyl chloride (CAS 2031268-98-9)
- Des-Ile27-Tirzepatide (CAS CATO-CPTD788946)
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