4-Fluoro-3-methylphenyl trifluoromethanesulfonate CAS 1446016-90-5
| CAS No. | 1446016-90-5 |
| Molecular Formula | C8H6F4O3S |
| Molecular Weight | 258.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 258.19 g/mol gives 4-Fluoro-3-methylphenyl trifluoromethanesulfonate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
4-Fluoro-3-methylphenyl trifluoromethanesulfonate (CAS 1446016-90-5) is a high-purity analytical reference standard with the molecular formula C8H6F4O3S and a molecular weight of 258.19 g/mol.
Owing to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, 4-Fluoro-3-methylphenyl trifluoromethanesulfonate is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 258.19 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-Fluoro-3-methylphenyl trifluoromethanesulfonate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H6F4O3S |
| Molecular Weight | 258.19 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
| Sulfur Atoms | 1 |
Related Fluoro Standards
- 2-Fluoro-3-methylphenyl trifluoromethanesulfonate (CAS 1446016-74-5)
- 1-Fluoro-7-nitroacridin-9(10H)-one (CAS 116333-44-9)
- 5-Fluoro-9-oxo-9H-xanthene-2-carboxylic acid (CAS 1263212-52-7)
- 5-Fluoro-3,6-dihydro-2,6-dioxo-3-(tetrahydro-2-furanyl)-1(2H)-pyrimidineacetic acid (CAS 872103-36-1)
- 5-(4-Fluoro-3-(trifluoromethyl)phenyl)pyrimidin-2-ol (CAS 1261904-80-6)
- 5-(2-Fluoro-3-(trifluoromethyl)phenyl)pyrimidin-2-ol (CAS 1261987-33-0)
- 5-(4-Fluoro-3-(trifluoromethyl)phenyl)furan-2-carbaldehyde (CAS 306936-05-0)
- 6-(4-Fluoro-3-(trifluoromethyl)phenyl)pyridazin-3(2H)-one (CAS 69713-92-4)
Recommended Standards
- 2,3,4,5,6-Pentafluoro-4'-methyl-1,1'-biphenyl (CAS 14621-04-6)
- 1-Benzyl-3,4-bis(chloromethyl)pyrrolidine (CAS 1416351-90-0)
- Diethyl 2-(2,2,2-trifluoro-1-hydroxyethyl)malonate (CAS 161361-20-2)
- 1-(Difluoro(2-fluorophenyl)methyl)-2,4-difluorobenzene (CAS 1374659-23-0)
- 1-(2-Chlorobenzyl)azetidine-2-carboxylic acid (CAS 1041177-46-1)
- 6-(Difluoromethyl)-3-fluoro-4-methylpyridin-2-amine (CAS 1804948-08-0)
- 3-Chloro-4-(trifluoromethyl)benzyl bromide (CAS 361393-92-2)
- 5-{[4-(trifluoromethoxy)anilino]carbonyl}-2,1,3-benzoxadiazol-1-ium-1-olate (CAS 680211-77-2)
- N-Nitroso Amoxicillin Impurity K (CAS CATO-C4X-114880)
- 1-(6-Chloro-5-methylpyridin-3-yl)ethan-1-amine (CAS 1270546-11-6)
- (2S,4R)-4-((tert-Butoxycarbonyl)amino)-1-methylpyrrolidine-2-carboxylic acid hydrochloride (CAS 1777812-68-6)
- 177352-81-7 Galanin (1-13)-Mastoparan MFCD02264772 (CAS 177352-81-7)
- 2-Bromomethyl-isonicotinic acid methyl ester hydrobromide (CAS 1956366-21-4)
- Semaglutide impurity 106 (CAS CATO-C4X-2226106)
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