5-(4-Ethoxy-3-nitrophenyl)-1,3,4-oxadiazol-2-amine CAS 144631-43-6
| CAS No. | 144631-43-6 |
| Molecular Formula | C10H10N4O4 |
| Molecular Weight | 250.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 5-(4-Ethoxy-3-nitrophenyl)-1,3,4-oxadiazol-2-amine (C10H10N4O4) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
5-(4-Ethoxy-3-nitrophenyl)-1,3,4-oxadiazol-2-amine (CAS 144631-43-6) is a high-purity analytical reference standard with the molecular formula C10H10N4O4 and a molecular weight of 250.21 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-(4-Ethoxy-3-nitrophenyl)-1,3,4-oxadiazol-2-amine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H10N4O4 |
| Molecular Weight | 250.21 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Nitrogen Atoms | 4 |
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Recommended Standards
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- 5-(Difluoromethyl)-2-fluoro-3-nitropyridin-4-amine (CAS 1805062-32-1)
- 2-(3-Chlorophenyl)-2,2-difluoroethanethioamide (CAS 1334146-97-2)
- Paeonol (CAS 552-41-0)
- 6,10-dithia-2,4,12-triazatricyclo[7.3.0.0³,⁷]dodeca-1,3(7),4,8,11-pentaene-5,11-diamine (CAS 27052-52-4)
- Methyl 3-aminooxolane-3-carboxylate (CAS 1182717-26-5)
- 4-Amino-5-methyl-1H-pyrazole-3-carbonitrile (CAS 28745-14-4)
- Tirzepatide Impurity 13 (CAS CATO-C4X-324013)
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