3-Chloro-4-(chloromethyl)isoquinoline hydrochloride CAS 1446346-72-0
| CAS No. | 1446346-72-0 |
| Molecular Formula | C10H7Cl2N |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
3-Chloro-4-(chloromethyl)isoquinoline hydrochloride (CAS 1446346-72-0), molecular formula C10H7Cl2NHCl and molecular weight 248.53 g/mol, is a CATO reference standard with documented purity and traceability.
3-Chloro-4-(chloromethyl)isoquinoline hydrochloride (C10H7Cl2NHCl) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO manufactures 3-Chloro-4-(chloromethyl)isoquinoline hydrochloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H7Cl2N HCl |
| Molecular Weight | 248.53 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
- 3-Amino-4,6-difluoro-1H-indazole (CAS 1197193-24-0)
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- (S)-3-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-2-(4-methylbenzyl)propanoic acid (CAS 1260605-80-8)
- 1,4-Bis(chloromethyl)-2-fluorobenzene (CAS 127865-67-2)
- 5-(4-bromophenyl)-2-(chloromethyl)-1,3-oxazole (CAS 64640-17-1)
- Ruxolitinib Impurity 77 (CAS 3016399-21-3)
- 3-BRomo-4-methylphenyl acetate (CAS 1695460-92-4)
- Methyl 7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyridine-3-carboxylate (CAS 1822620-12-1)
- Semaglutide impurity 197 (CAS CATO-C4X-2226197)
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