3-Chloro-4-(chloromethyl)isoquinoline CAS 1446396-06-0
| CAS No. | 1446396-06-0 |
| Molecular Formula | C10H7Cl2N |
| Molecular Weight | 212.08 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-Chloro-4-(chloromethyl)isoquinoline (CAS 1446396-06-0), molecular formula C10H7Cl2N and molecular weight 212.08 g/mol, is a CATO reference standard with documented purity and traceability.
3-Chloro-4-(chloromethyl)isoquinoline (C10H7Cl2N) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3-Chloro-4-(chloromethyl)isoquinoline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H7Cl2N |
| Molecular Weight | 212.08 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 7-Chloro-3-(chloromethyl)isoquinoline (CAS 1079652-68-8)
- 7-Chloro-6-(chloromethyl)quinoline (CAS 1244948-88-6)
- 5-Chloro-8-(chloromethyl)quinoline (CAS 1340315-94-7)
- 6-Chloro-2-(chloromethyl)quinoline (CAS 137898-64-7)
- 1-chloro-3-(chloromethyl)isoquinoline (CAS 1803582-29-7)
- 3-Chloro-6-(chloromethyl)quinoline (CAS 1860892-43-8)
- 4-Chloro-2-(chloromethyl)quinoline (CAS 303224-88-6)
- 4-Chloro-2-nitrobenzyl chloride 4-chloro-1-(chloromethyl)-2-nitrobenzene 938-71-6 (CAS 938-71-6)
Recommended Standards
- 2,8-Dichloro-5-methylquinoline (CAS 1432322-83-2)
- 2,4-Dichloro-5-methylquinoline (CAS 153749-71-4)
- 1-(3,5-Dichloro-phenyl)-1H-pyrrole (CAS 154458-86-3)
- 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2,3-thiadiazole (CAS 1346808-45-4)
- Methyl 5-hydroxythiazole-2-carboxylate (CAS 1352395-02-8)
- 3,5-Diethylphenol (CAS 1197-34-8)
- 5-Amino-2-cyclobutyloxazole-4-carbonitrile (CAS 909077-19-6)
- 6-Fluorobenzo[b]thiophene-2-carbonitrile (CAS 1517197-72-6)
- N-(2-chloro-5-cyanophenyl)acetamide (CAS 53312-92-8)
- 2-(5-Phenyl-1H-tetrazol-1-yl)-3-(thiophen-2-yl)acrylic acid (CAS 36283-09-7)
- 1-(1-Isobutylpyrrolidin-3-yl)-N-methylmethanamine (CAS 887405-45-0)
- N-((1,4,5-trimethyl-1H-imidazol-2-yl)methyl)ethanamine (CAS 921074-60-4)
- 4-(Diethylsulfamoyl)benzoyl chloride (CAS 29171-71-9)
- Insulin Degludec Impurity 12 (CAS CATO-C4X-215712)
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