4-Bromo-5-methyl-2-(trifluoromethyl)thiazole CAS 1446412-91-4
| CAS No. | 1446412-91-4 |
| Molecular Formula | C5H3BrF3NS |
| Molecular Weight | 246.05 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-Bromo-5-methyl-2-(trifluoromethyl)thiazole is closely related to a nitrile group, sulfur-containing functionality, fluorine/bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-Bromo-5-methyl-2-(trifluoromethyl)thiazole (CAS 1446412-91-4), molecular formula C5H3BrF3NS and molecular weight 246.05 g/mol, is a CATO reference standard with documented purity and traceability.
4-Bromo-5-methyl-2-(trifluoromethyl)thiazole (C5H3BrF3NS) contains a nitrile group, sulfur-containing functionality, fluorine/bromine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-Bromo-5-methyl-2-(trifluoromethyl)thiazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H3BrF3NS |
| Molecular Weight | 246.05 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Bromo Standards
- 2-Bromo-5-methyl-4-(trifluoromethyl)thiazole (CAS 1289062-40-3)
- 5-Bromo-4-(trifluoromethyl)thiophen-2-amine (CAS 1368301-44-3)
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- 4-Bromo-3-(difluoromethyl)-1H-indole (CAS 1780756-02-6)
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- 6-Bromo-2-(difluoromethyl)-1H-indole (CAS 1780771-02-9)
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Recommended Standards
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- 1,3-Dimethyl-5-(2-oxo-2-(piperazin-1-yl)ethyl)imidazolidine-2,4-dione (CAS 1009673-49-7)
- Methyl 2-(5-imino-2,5-dihydro-1h-1,2,4-triazol-3-yl)acetate hydrochloride (CAS 1279219-32-7)
- 3-Nitro-4-(4-phenylpiperidin-1-yl)-2H-chromen-2-one (CAS 294853-41-1)
- 17B(H),21B(H)-Hop-22(29)-en-3-one (CAS 25615-11-6)
- 1,3-Dibromo-2-methoxypropane (CAS 26581-42-0)
- 3,3'-Diselanediylbis(propan-1-ol) (CAS 23243-47-2)
- (1-(4-Chlorophenyl)-1H-1,2,3-triazol-4-yl)methyl ethylcarbamate (CAS 338419-15-1)
- Semaglutide impurity 205 (CAS CATO-C4X-2226205)
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