Tenofovir Disoproxil USP Related Compound B CAS 1446486-33-4
| CAS No. | 1446486-33-4 |
| Molecular Formula | C8H9N5 |
| Molecular Weight | 175.19 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 175.19 g/mol gives Tenofovir Disoproxil USP Related Compound B distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Tenofovir Disoproxil USP Related Compound B (CAS 1446486-33-4) is a certified pharmaceutical impurity reference standard with the molecular formula C8H9N5 and a molecular weight of 175.19 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, Tenofovir Disoproxil USP Related Compound B is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 175.19 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Tenofovir Disoproxil USP Related Compound B under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H9N5 |
| Molecular Weight | 175.19 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Nitrogen Atoms | 5 |
Related Tenofovir Standards
- Tenofovir Impurity C13 (CAS 1464851-21-5)
- Tenofovir disoproxil Impurity 19 (CAS 4121-39-5)
- Tenofovir disoproxil Impurity 85 (CAS 707-99-3)
- Tenofovir disoproxil Impurity 58 (CAS 1611-31-0)
- Tenofovir disoproxil Impurity 90 (CAS 3084-40-0)
- Tenofovir Impurity 144 (CAS 2715-68-6)
- Tenofovir alafenamide impurity N1 (CAS 16958-60-4)
- Tenofovir Impurity 110 (CAS 20776-34-5)
Recommended Standards
- Rizatriptan Impurity 24 (CAS 119192-11-9)
- L-Citrulline (CAS 372-75-8)
- N-nitroso 5,6-dimethylbenzimidazole (CAS CATO-C4X-187428)
- D-Citrulline (CAS 13594-51-9)
- Atorvastatin Impurity 96 (CAS CATO-C4X-113296)
- Dotinurad Impurity 144 (CAS 74953-20-1)
- Sodium Cromoglicate Impurity 27 (CAS CATO-C4X-201127)
- 2-(1,3-Dioxolan-2-yl)-1-phenylethan-1-one (CAS 55337-55-8)
- N-((1H-Pyrrol-2-yl)methyl)-N-benzyl-1-phenylmethanamine (CAS 6642-04-2)
- (S)-2-amino-2-(2-fluoro-3-(trifluoromethyl)phenyl)ethan-1-ol (CAS 1212901-19-3)
- 4-(4,5-Dihydro-1H-imidazol-2-yl)-N-methylaniline (CAS 799292-23-2)
- methyl 5-methyl-2,4-dioxo-1H-pyrimidine-6-carboxylate (CAS 78202-43-4)
- 4-amino-2-methoxy-6-methylpyrimidine-5-carbonitrile (CAS 209849-42-3)
- Semaglutide Impurity 10 (CAS CATO-C4X-222610)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com