(5-Fluoro-1H-benzimidazol-2-yl)methanamine hydrochloride CAS 1446513-97-8
| CAS No. | 1446513-97-8 |
| Molecular Formula | C8H8FN3 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
(5-Fluoro-1H-benzimidazol-2-yl)methanamine hydrochloride (CAS 1446513-97-8) is a high-purity analytical reference standard with the molecular formula C8H8FN3HCl and a molecular weight of 201.63 g/mol.
(5-Fluoro-1H-benzimidazol-2-yl)methanamine hydrochloride (C8H8FN3HCl) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), (5-Fluoro-1H-benzimidazol-2-yl)methanamine hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H8FN3 HCl |
| Molecular Weight | 201.63 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
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Recommended Standards
- tert-Butyl 4-(piperidin-4-ylmethyl)piperazine-1-carboxylate (CAS 1211568-27-2)
- (7-Chloro-2,3-dihydrofuro[2,3-c]pyridin-3-yl)methanol (CAS 174469-04-6)
- 3-Nitrodibenzo[b,d]furan (CAS 5410-97-9)
- Sofosbuvir Impurity 52 (CAS CATO-C4X-105252)
- Methyl 4-acetoxy-3-oxobutanoate (CAS 87730-99-2)
- Methyl 2-(2-bromoacetamido)benzoate (CAS 5946-43-0)
- 3-(4-Bromophenyl)-1,4-dimethyl-1h-pyrazol-5-amine (CAS 1152653-72-9)
- 4-Iodo-2-methylpyrazole-3-carboxamide (CAS 292855-29-9)
- 5,6-Dimethylindole (CAS 30877-30-6)
- Acetyl Tetrapeptide-11 (CAS 928006-88-6)
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