3-(Trifluoromethyl)pyrrolidine-1-sulfonyl chloride CAS 1446526-74-4
| CAS No. | 1446526-74-4 |
| Molecular Formula | C5H7ClF3NO2S |
| Molecular Weight | 237.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 237.63 g/mol gives 3-(Trifluoromethyl)pyrrolidine-1-sulfonyl chloride distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 3-(Trifluoromethyl)pyrrolidine-1-sulfonyl chloride (CAS 1446526-74-4), a certified reference material (molecular formula C5H7ClF3NO2S, MW 237.63 g/mol) for analytical method development and quality control.
Based on its molecular formula C5H7ClF3NO2S, 3-(Trifluoromethyl)pyrrolidine-1-sulfonyl chloride contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic functional-group stretching vibrations in infrared spectroscopy. The molecular weight of 237.63 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3-(Trifluoromethyl)pyrrolidine-1-sulfonyl chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H7ClF3NO2S |
| Molecular Weight | 237.63 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Trifluoromethyl Standards
- (S)-3-(Trifluoromethyl)pyrrolidine-1-sulfonyl chloride (CAS 1446526-76-6)
- 4-((Trifluoromethyl)thio)benzothioamide (CAS 926269-75-2)
- 949507-76-0 2-Methyl-6-trifluoromethyl-4-quinolinol MFCD00272465 (CAS 949507-76-0)
- 3-(5-Methyl-3-(trifluoromethyl)-1h-pyrazol-1-yl)propanethioamide (CAS 1006320-12-2)
- 3-(3-(Trifluoromethyl)-1h-pyrazol-1-yl)butanethioamide (CAS 1006348-58-8)
- 3-(3-Methyl-5-(trifluoromethyl)-1h-pyrazol-1-yl)propanethioamide (CAS 1006348-83-9)
- 1-[4-(trifluoromethyl)-1,3-thiazol-2-yl]piperazine (CAS 107507-53-9)
- 2-{[6-methyl-4-(trifluoromethyl)-2-pyridyl]thio}ethan-1-ol (CAS 245728-41-0)
Recommended Standards
- 2-Trifluoromethylpyrrolidine-1-sulfonyl chloride (CAS 1389314-96-8)
- (R)-2-Trifluoromethylpyrrolidine-1-sulfonyl chloride (CAS 1389310-08-0)
- 2-Chloro-6-trifluoromethylbenzothiazole (CAS 159870-86-7)
- (S)-2-Trifluoromethylpyrrolidine-1-sulfonyl chloride (CAS 1310732-44-5)
- N-Benzyl-2-(diphenylphosphoryl)acetamide (CAS 90304-93-1)
- 1-methyl-4-oxopiperidine-3-carbaldehyde (CAS 1194575-07-9)
- 1-(2,4-Dichlorophenyl)-2-(1H-imidazol-2-yl)ethan-1-one (CAS 252950-14-4)
- Methyl 3-((2,6-dichlorobenzyl)oxy)thieno[2,3-b]pyridine-2-carboxylate (CAS 338419-40-2)
- 1-(2-Chloropyrimidin-4-yl)piperidine-4-carboxamide (CAS 1250763-75-7)
- 2,2,5,7,8-pentamethylchroman-6-sulfonyl chloride (CAS 112160-39-1)
- 2-(1-hydroxyethyl)-1,3-thiazole-5-carbaldehyde (CAS 1803605-24-4)
- 2-Nitro-5-(((4-nitrophenyl)sulfonyl)methyl)furan (CAS 61266-29-3)
- 8-Bromo-4-chloropyrido[4,3-d]pyrimidine (CAS 1269421-61-5)
- Semaglutide-d15 (CAS 910463-68-2(non-labelled))
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