3-(4-Fluoro-2-hydroxyphenyl)-3-phenylisobenzofuran-1(3H)-one CAS 144654-37-5

Purity 97%+In StockPharmaceutical Standards
CAS No.144654-37-5
Molecular FormulaC20H13FO3
Molecular Weight320.31 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3-(4-Fluoro-2-hydroxyphenyl)-3-phenylisobenzofuran-1(3H)-one CAS 144654-37-5 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 320.31 g/mol gives 3-(4-Fluoro-2-hydroxyphenyl)-3-phenylisobenzofuran-1(3H)-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

3-(4-Fluoro-2-hydroxyphenyl)-3-phenylisobenzofuran-1(3H)-one (CAS 144654-37-5), molecular formula C20H13FO3 and molecular weight 320.31 g/mol, is a CATO reference standard with documented purity and traceability.

3-(4-Fluoro-2-hydroxyphenyl)-3-phenylisobenzofuran-1(3H)-one (C20H13FO3) contains a steroid core, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC20H13FO3
Molecular Weight320.31 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)14.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1998
Halogen ContentF-containing

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