(S)-2-(3-(difluoromethyl)-4-fluoro-5-(trifluoromethyl)phenyl)pyrrolidine CAS 1447005-57-3
| CAS No. | 1447005-57-3 |
| Molecular Formula | C12H11F6N |
| Molecular Weight | 283.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures (S)-2-(3-(difluoromethyl)-4-fluoro-5-(trifluoromethyl)phenyl)pyrrolidine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
(S)-2-(3-(difluoromethyl)-4-fluoro-5-(trifluoromethyl)phenyl)pyrrolidine (CAS 1447005-57-3), molecular formula C12H11F6N and molecular weight 283.21 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution, (S)-2-(3-(difluoromethyl)-4-fluoro-5-(trifluoromethyl)phenyl)pyrrolidine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 283.21 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C12H11F6N |
| Molecular Weight | 283.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related S Standards
- 2-(Difluoromethyl)-3-methoxy-5-nitropyridine-6-sulfonamide (CAS 1361706-13-9)
- 2-(Difluoromethyl)-4-methoxy-3-nitropyridine-6-sulfonamide (CAS 1361736-91-5)
- 2-(Difluoromethyl)-6-methoxy-3-nitropyridine-5-sulfonamide (CAS 1361737-00-9)
- 2-(Difluoromethyl)-6-methoxy-4-nitropyridine-3-sulfonamide (CAS 1361770-39-9)
- 2-(Difluoromethyl)-4-methoxy-3-nitropyridine-5-sulfonamide (CAS 1361797-29-6)
- 2-(Difluoromethyl)-6-methoxy-5-nitropyridine-3-sulfonamide (CAS 1361819-82-0)
- 2-(Difluoromethyl)-5-methoxy-3-nitropyridine-6-sulfonamide (CAS 1361870-84-9)
- 2-(Difluoromethyl)-4-methoxy-5-nitropyridine-3-sulfonamide (CAS 1361886-09-0)
Recommended Standards
- 2-(Difluoromethyl)-3-methoxy-4-nitropyridine-6-sulfonamide (CAS 1361912-01-7)
- (R)-2-(3-(difluoromethyl)-4-fluoro-5-(trifluoromethyl)phenyl)pyrrolidine (CAS 1447147-76-3)
- 1-(4-Bromo-2,6-dimethylphenyl)piperidin-3-amine (CAS 1493326-10-5)
- (1-(3,5-Bis(trifluoromethyl)phenyl)cyclopropyl)methanamine (CAS 1502854-87-6)
- diethyl (1,1-difluoro-2-hydroxy-2-(pyridin-2-yl)ethyl)phosphonate (CAS 191014-04-7)
- rel-(3R,4S)-Methyl 3-ethyl-4-hydrazinylpiperidine-1-carboxylate (CAS 1263281-41-9)
- 2-(Pyridin-4-yl)-5,6,7,8-tetrahydro-4H-pyrazolo[1,5-a][1,4]diazepin-4-one (CAS 723338-88-3)
- 1-Cyclobutylpentan-1-amine (CAS 1270489-69-4)
- 2-(2-Ethoxyacetamido)-4-methoxybenzene-1-sulfonyl chloride (CAS 1427379-29-0)
- 3-Chloro-2-cyano-5-(trifluoromethyl)pyridine 1-Oxide (CAS 1823184-13-9)
- 3-Cyclopropoxy-5-formylisonicotinamide (CAS 1243466-09-2)
- 3-(4-Propylphenyl)azetidine (CAS 1260899-33-9)
- 3,5-Dichloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS 1257641-28-3)
- Semaglutide impurity 56 (CAS CATO-C4X-222656)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com