4-Amino-3-(3,5-dichlorophenyl)-1H-1,2,4-triazole-5(4H)-thione CAS 144729-37-3
| CAS No. | 144729-37-3 |
| Molecular Formula | C8H6Cl2N4S |
| Molecular Weight | 261.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-Amino-3-(3,5-dichlorophenyl)-1H-1,2,4-triazole-5(4H)-thione is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-Amino-3-(3,5-dichlorophenyl)-1H-1,2,4-triazole-5(4H)-thione (CAS 144729-37-3) is a high-purity analytical reference standard with the molecular formula C8H6Cl2N4S and a molecular weight of 261.13 g/mol.
4-Amino-3-(3,5-dichlorophenyl)-1H-1,2,4-triazole-5(4H)-thione (C8H6Cl2N4S) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-Amino-3-(3,5-dichlorophenyl)-1H-1,2,4-triazole-5(4H)-thione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H6Cl2N4S |
| Molecular Weight | 261.13 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Amino Standards
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