Clopidogrel Hydrochloride EP Impurity A CAS 144750-42-5
| CAS No. | 144750-42-5 |
| Molecular Formula | C15H14ClNO2S |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Clopidogrel Hydrochloride EP Impurity A (CAS 144750-42-5), a pharmacopoeial impurity reference standard (molecular formula C15H14ClNO2SHCl, MW 344.25 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C15H14ClNO2SHCl, Clopidogrel Hydrochloride EP Impurity A contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 344.25 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Clopidogrel Hydrochloride EP Impurity A meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H14ClNO2S HCl |
| Molecular Weight | 344.25 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Clopidogrel Standards
- Clopidogrel Impurity 74 (CAS 1008008-56-7)
- Clopidogrel Impurity 82 (CAS 1015247-87-6)
- rac-Clopidogrel EP Impurity A HCl (CAS 1015247-88-7)
- rac Clopidogrel [(tert-Butylcarbonyl)oxy]methyl ester (CAS 1043913-82-1)
- 2-Oxo Clopidogrel (Mixture of Diastereomers) (CAS 109904-27-0)
- Clopidogrel Impurity 42 (CAS 109904-36-1)
- cis-Clopidogrel glutathione disulfide, mixture of diastereomers (CAS 1118605-95-0)
- Clopidogrel Impurity 48 (CAS 111954-31-5)
Recommended Standards
- Pyridoxine Impurity 17 DiHCl (CAS CATO-C4X-187748)
- Fosinopril impurity 4 (CAS CATO-C4X-16524)
- Fasudil Impurity 13 (CAS 748752-50-3)
- (2E)-3-(6-Bromo-2H-1,3-benzodioxol-5-yl)-N-(2-methylbutan-2-yl)prop-2-enamide (CAS 478078-31-8)
- N-[2-(1,3-Dimethyl-5-phenoxy-1H-pyrazol-4-yl)ethyl]benzenesulfonamide (CAS 477711-46-9)
- (S)-N-(1-((1,3,4-Thiadiazol-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)thiomorpholine-4-carboxamide (CAS 1246076-02-7)
- 6-Hydroxy-1-(2-methoxyethyl)-4-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile (CAS 39108-50-4)
- 2-chloro-10-[3-(dimethylamino)propyl]-10h-phenothiazin-1-ol 41138-92-5 AR-1E0039 (CAS 41138-92-5)
- 3-(4-Bromophenoxy)propanenitrile (CAS 118449-57-3)
- Tirzepatide Impurity 45 (CAS CATO-C4X-324045)
Why CATO?
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