Ethyl 2-(5-bromopyridin-2-yl)pyrimidine-5-carboxylate CAS 1447608-00-5
| CAS No. | 1447608-00-5 |
| Molecular Formula | C12H10BrN3O2 |
| Molecular Weight | 308.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Ethyl 2-(5-bromopyridin-2-yl)pyrimidine-5-carboxylate (C12H10BrN3O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Ethyl 2-(5-bromopyridin-2-yl)pyrimidine-5-carboxylate (CAS 1447608-00-5), molecular formula C12H10BrN3O2 and molecular weight 308.13 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures Ethyl 2-(5-bromopyridin-2-yl)pyrimidine-5-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H10BrN3O2 |
| Molecular Weight | 308.13 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 3 |
Related Ethyl Standards
- 1-(5-Bromopyridin-2-yl)-5-cyclopropyl-1h-pyrazole-4-carboxylic acid (CAS 1496108-57-6)
- 2-(5-Bromopyridin-3-yl)-6-chloro-1h-1,3-benzodiazole (CAS 1035818-95-1)
- 3-(6-Bromopyridin-2-yl)-6-chloroimidazo[1,2-a]pyridine (CAS 1044733-65-4)
- 2-(6-Bromopyridin-3-yl)-5-chloro-1H-benzo[d]imidazole (CAS 1261236-56-9)
- 2-((2-Bromopyridin-3-yl)oxy)benzo[d]thiazole (CAS 1065484-73-2)
- 4-((6-Bromopyridin-3-yl)sulfonyl)morpholine (CAS 1216081-03-6)
- (R)-2-((5-Bromopyridin-3-yl)amino)-2-phenylacetic acid 1569320-29-1 (CAS 1569320-29-1)
- Benzyl (6-bromopyridin-3-yl)carbamate (CAS 175393-05-2)
Recommended Standards
- 10-Bromo-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepine-2-carboxamide (CAS 1401304-15-1)
- 3-(Benzyloxy)-5-bromopicolinic acid (CAS 1393534-89-8)
- 2-(2-Bromophenoxy)-4-methyl-1-nitrobenzene (CAS 1516187-55-5)
- 1-(Benzyloxy)-3-bromo-2-nitrobenzene (CAS 1314091-92-3)
- (Z)-Hept-2-en-2-ylboronic acid (CAS 118967-15-0)
- benzyl 3-[(4-methylbenzenesulfonyl)oxy]azetidine-1-carboxylate (CAS 939759-24-7)
- 2-(3-Methoxyphenyl)ethanamine hydrochloride (CAS 2039-54-5)
- 1-[2-(Propan-2-yl)phenyl]piperazine (CAS 119695-82-8)
- 3-[3,5-Dimethyl-1-(4-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)-1H-pyrazol-4-yl]propanoic acid (CAS 1170850-14-2)
- N-Ethyl-5-(((piperidin-4-ylmethyl)amino)methyl)pyrimidin-2-amine (CAS 1279203-65-4)
- LCZ-696 Impurity 74 (CAS CATO-C4X-169674)
- 2-(2-(Benzyloxy)-5-(tert-butyl)phenyl)-2-methylpropan-1-ol (CAS 1246213-29-5)
- (2-Amino-5-methylthiophen-3-yl)(4-chlorophenyl)methanone (CAS 436093-32-2)
- D-Ser39-Tirzepatide (CAS CATO-CPTD788694)
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