Ethyl 4-chloro-7-nitroquinoline-2-carboxylate CAS 1447608-14-1
| CAS No. | 1447608-14-1 |
| Molecular Formula | C12H9ClN2O4 |
| Molecular Weight | 280.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Ethyl 4-chloro-7-nitroquinoline-2-carboxylate is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Ethyl 4-chloro-7-nitroquinoline-2-carboxylate (CAS 1447608-14-1), molecular formula C12H9ClN2O4 and molecular weight 280.66 g/mol, is a CATO reference standard with documented purity and traceability.
Ethyl 4-chloro-7-nitroquinoline-2-carboxylate (C12H9ClN2O4) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures Ethyl 4-chloro-7-nitroquinoline-2-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H9ClN2O4 |
| Molecular Weight | 280.66 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Ethyl Standards
- Ethyl 4-chloro-6-nitroquinoline-3-carboxylate (CAS 103514-54-1)
- 2-((4-Chloro-6-methoxypyrimidin-2-yl)oxy)benzoic acid (CAS 110284-77-0)
- 3-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-1,2,4-thiadiazol-5-amine (CAS 1179362-69-6)
- 3-Chloro-2-(1H-1,2,4-triazol-3-ylsulfanyl)-5-(trifluoromethyl)pyridine (CAS 123822-41-3)
- Ethyl 4-chloro-8-nitroquinoline-3-carboxylate (CAS 131548-98-6)
- Ethyl 4-chloro-5-nitroquinoline-2-carboxylate (CAS 1447606-60-1)
- 2-(6-Chloro-3-hydroxyquinoline-2-carboxamido)acetic acid (CAS 189359-08-8)
- Ethyl 4-chloro-7-nitroquinoline-3-carboxylate (CAS 19499-22-0)
Recommended Standards
- Methyl 2-((3-(4-chlorophenyl)isoxazol-5-yl)amino)-2-oxoacetate (CAS 1622069-59-3)
- Methyl 1-(4-chlorophenyl)-4-hydroxy-6-oxo-1,6-dihydropyridazine-3-carboxylate (CAS 121582-56-7)
- 1-(3-Chlorophenyl)-4-methoxy-6-oxo-1,6-dihydropyridazine-3-carboxylic acid (CAS 339030-37-4)
- 2-(2-(1,3-Dioxoisoindolin-2-yl)acetamido)acetyl chloride (CAS 59180-28-8)
- METHYL 2-FORMYLTHIOPHENE-3-CARBOXYLATE (CAS 24647-82-3)
- 1-(1-(4-(p-Tolyloxy)butyl)-1H-benzo[d]imidazol-2-yl)propan-1-ol (CAS 876901-31-4)
- 2-[3,6-dicyclopropyl-4-(difluoromethyl)-1h-pyrazolo[3,4-b]pyridin-1-yl]acetic acid (CAS 937607-23-3)
- 1-(2-Chlorophenyl)-5-(thiophen-2-yl)-1H-pyrazole (CAS 1269291-36-2)
- Methyl 4-(dimethylamino)-3-sulfamoylbenzoate (CAS 1274758-60-9)
- 2-[(4-aminophenyl)formamido]acetamide (CAS 46319-19-1)
- 1H-Pyrazolo[3,4-β]pyridine-3-acetic Acid (CAS 1155847-27-0)
- 2-((Isobutylthio)methyl)-6-oxo-1,6-dihydropyrimidine-5-carboxylic acid (CAS 1493027-16-9)
- Quinethazone (CAS 73-49-4)
- Insulin Glargine Metabolite M2 (CAS CATO-CPTD788867)
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