ethyl 6,6-difluorospiro[2.5]octane-1-carboxylate CAS 1447942-88-2
| CAS No. | 1447942-88-2 |
| Molecular Formula | C11H16F2O2 |
| Molecular Weight | 218.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including ethyl 6,6-difluorospiro[2.5]octane-1-carboxylate.
ethyl 6,6-difluorospiro[2.5]octane-1-carboxylate (CAS 1447942-88-2), molecular formula C11H16F2O2 and molecular weight 218.24 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, ethyl 6,6-difluorospiro[2.5]octane-1-carboxylate is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 218.24 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H16F2O2 |
| Molecular Weight | 218.24 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
Related ethyl Standards
- Ethyl 1,1-Difluorospiro[2.5]octane-6-carboxylate (CAS 1447942-59-7)
- 6,8-Difluorospiro[chroman-2,1'-cyclobutan]-4-one (CAS 934554-68-4)
- 6,8-Difluorospiro[chroman-2,1'-cyclobutan]-4-amine (CAS 934554-70-8)
- 5,5-difluorospiro[6H-pyrano[3,4-b]pyridine-8,3'-tetrahydrofuran] (CAS 2761389-78-8)
- methyl 6,6-difluorospiro[3.3]heptane-2-carboxylate (CAS 1419101-40-8)
- 1,1-Difluorospiro[2.5]octane-6-carboxylic Acid (CAS 1447943-49-8)
- 6,6-Difluorospiro[2.5]octane-1-carboxylic acid (CAS 1447943-53-4)
- (1S)-6,6-Difluorospiro[2.5]octane-1-carboxylic acid (CAS 1645564-71-1)
Recommended Standards
- 2-(Methylthio)-7-oxo-1,7-dihydropyrido[2,3-d]pyrimidine-6-carbonitrile (CAS 1537216-36-6)
- 1-(Cyclopropylmethyl)-4,4-difluorocyclohexane-1-carboxylic acid (CAS 1389315-09-6)
- 3-amino-7,9-difluoro-1,3,4,5-tetrahydro-1-benzazepin-2-one (CAS 1622853-51-3)
- 5-(1,3-benzothiazol-2-yl)-1,3,4-oxadiazol-2-amine (CAS 1350988-83-8)
- Methyl 3-Bromo-5-formylbenzoate (CAS 377734-27-5)
- 2-(3-cyano-1H-1,2,4-triazol-1-yl)propanoic acid (CAS 1249550-68-2)
- 2-(3-Methylpyridin-4-yl)acetonitrile (CAS 1000557-13-0)
- 4,7-dioxa-13-azatricyclo[8.5.0.0^{3,8}]pentadeca-1(10),2,8-trien-12-one (CAS 1209081-98-0)
- 1-Bromo-4-hydroxymethylnaphthalene (CAS 56052-26-7)
- 3-Pyrrolidinyl 2,2,2-trichloroacetatehydrochloride (CAS 1219948-50-1)
- N-[(4-Cyanophenyl)(4-fluorophenyl)methyl]acetamide (CAS 1365272-53-2)
- 3-Amino-4-cyano-1-methyl-1h-pyrrole-2-carboxylic acid (CAS 923255-40-7)
- Sodium 2-phenyl-4,5,6,7-tetrahydro-2h-indazole-3-carboxylate (CAS 1170796-46-9)
- Semaglutide impurity 211 (CAS CATO-C4X-2226211)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com