2-(4,4-Difluorocyclohexyl)-2-methylpropanoic acid CAS 1447944-50-4
| CAS No. | 1447944-50-4 |
| Molecular Formula | C10H16F2O2 |
| Molecular Weight | 206.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies 2-(4,4-Difluorocyclohexyl)-2-methylpropanoic acid (CAS 1447944-50-4), a certified reference material (molecular formula C10H16F2O2, MW 206.23 g/mol) for analytical method development and quality control.
The molecular framework of 2-(4,4-Difluorocyclohexyl)-2-methylpropanoic acid (C10H16F2O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C10H16F2O2 |
| Molecular Weight | 206.23 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
Related Difluorocyclohexyl Standards
- Ethyl 2-(2,2-difluorocyclohexyl)acetate (CAS 1035559-58-0)
- Ethyl 2-(3,3-difluorocyclohexyl)acetate (CAS 1694540-47-0)
- Ethyl 2-(4,4-Difluorocyclohexyl)acetate (CAS 915213-54-6)
- 5-(4,4-difluorocyclohexyl)-1,3,4-oxadiazol-2-amine (CAS 1552763-97-9)
- 3-(4,4-difluorocyclohexyl)-1H-pyrazol-5-amine (CAS 1795287-42-1)
- 3-(4,4-Difluorocyclohexyl)aniline (CAS 478403-44-0)
- 4-(4,4-Difluorocyclohexyl)phenol (CAS 161553-81-7)
- 6-(4,4-Difluorocyclohexyl)pyridin-3-amine (CAS 2662572-48-5)
Recommended Standards
- Ethyl 3-trifluoromethylphenylsulfide (CAS 1447671-84-2)
- 2-((7-Amino-[1,2,4]triazolo[1,5-c]pyrimidin-5-yl)thio)acetonitrile (CAS 144105-14-6)
- 2-(3,3-Difluoro-5,5-dimethylcyclohexyl)acetic acid (CAS 1781057-81-5)
- Ethyl 2-cyclohexyl-2,2-difluoroacetate (CAS 134682-44-3)
- 4-Nitrophenyl-ethyleneglycol (CAS 88057-19-6)
- 3-Fluorocyclobutan-1-one (CAS 1415342-84-5)
- 3-(1,1-Dioxido-2H-benzo[e][1,2,4]thiadiazin-3-yl)propanoic acid (CAS 4826-22-6)
- 2-(4-Cyclopropyl-5-(methylthio)-4H-1,2,4-triazol-3-yl)ethanamine hydrochloride (CAS 1233025-89-2)
- rel-(4S,5R)-4-Amino-5-phenylpyrrolidin-2-one (CAS 1262791-40-1)
- 3-Amino-7-methyl-N-(2-methyl-4-nitrophenyl)thieno[2,3-b]quinoline-2-carboxamide (CAS 332885-30-0)
- (S)-2-(2,3-Dichlorobenzyl)piperazine (CAS 1240586-31-5)
- (S)-2-amino-3-(2-(trifluoromethyl)phenyl)propan-1-ol (CAS 944836-45-7)
- 3-(Ethoxycarbonyl)-1-(2-ethylphenyl)-5-methyl-4,5-dihydro-1h-pyrazole-5-carboxylic acid (CAS 1264043-12-0)
- Dendroaspis Natriuretic Peptide (CAS 255721-52-9)
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