3-Methyl-1,2,4-thiadiazole-5-carboxamide CAS 1448078-67-8
| CAS No. | 1448078-67-8 |
| Molecular Formula | C4H5N3OS |
| Molecular Weight | 143.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-Methyl-1,2,4-thiadiazole-5-carboxamide is closely related to an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3-Methyl-1,2,4-thiadiazole-5-carboxamide (CAS 1448078-67-8), molecular formula C4H5N3OS and molecular weight 143.17 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, 3-Methyl-1,2,4-thiadiazole-5-carboxamide is typically off-white to pale yellow liquid. Its solid-state physicochemical attributes — including a molecular weight of 143.17 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-Methyl-1,2,4-thiadiazole-5-carboxamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C4H5N3OS |
| Molecular Weight | 143.17 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1992 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Methyl Standards
- 4-methyl-1,2,3-thiadiaZole-5-carboxamide (CAS 175136-67-1)
- Methyl 1,3,4-thiadiazole-2-carboxylate (CAS 1330751-02-4)
- 4-Methyl-1,2,3-thiadiazole-5-carboxylic Acid (CAS 18212-21-0)
- 4-Methyl-1,2,5-thiadiazole-3-carboxylic acid (CAS 99390-23-5)
- 5-Methyl-1,2,3-thiadiazole-4-carboxylic acid (CAS 22097-10-5)
- 5-Methyl-1,3,4-thiadiazole-2-carboxylic Acid (CAS 501698-31-3)
- Methyl 1,2,3-thiadiazole-4-carboxylate (CAS 3989-35-3)
- Methyl 1,2,3-thiadiazole-5-carboxylate (CAS 81699-19-6)
Recommended Standards
- 5-Amino-4-isothiazolecarboxamide (CAS 1421637-53-7)
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- 5-Aminothiazole-2-carboxamide (CAS 134983-33-8)
- 3-Methyl Isonicotinic Acid-d6 (CAS 1346599-31-2)
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