6-((3-Chloro-4-fluorophenyl)sulfonyl)-6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidine CAS 1448132-92-0
| CAS No. | 1448132-92-0 |
| Molecular Formula | C12H9ClFN3O2S |
| Molecular Weight | 313.74 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-((3-Chloro-4-fluorophenyl)sulfonyl)-6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidine.
6-((3-Chloro-4-fluorophenyl)sulfonyl)-6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidine (CAS 1448132-92-0), molecular formula C12H9ClFN3O2S and molecular weight 313.74 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 6-((3-Chloro-4-fluorophenyl)sulfonyl)-6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidine is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 313.74 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 6-((3-Chloro-4-fluorophenyl)sulfonyl)-6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H9ClFN3O2S |
| Molecular Weight | 313.74 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 6-Chloro-2-(4-methoxyphenyl)quinoline-4-carboxylic acid (CAS 116734-25-9)
- N-(5-Chloro-2-methylphenyl)-6-(1H-pyrazol-1-yl)pyridazine-3-carboxamide (CAS 1351594-90-5)
- 4-Chloro-N-(2-methyl-4-oxoquinazolin-3(4H)-yl)benzamide (CAS 178919-58-9)
- (4E)-4-[(3-Chloro-4-methoxyphenyl)methylidene]-2-phenyl-4,5-dihydro-1,3-oxazol-5-one (CAS 861207-97-8)
- (5-Chloro-2-(3-(hydroxymethyl)-4H-1,2,4-triazol-4-yl)phenyl)(phenyl)methanone (CAS 54041-98-4)
- 2-(6-Chloro-1-methyl-4-oxo-1,4-dihydroquinolin-3-yl)benzoic acid (CAS 866135-92-4)
- 2-(6-Chloro-2-hydroxy-4-phenylquinolin-3-yl)acetic acid (CAS 51505-10-3)
- 2-Chloro-3-((2-methoxyphenyl)amino)naphthalene-1,4-dione (CAS 64505-74-4)
Recommended Standards
- N-(6-(1H-Imidazol-1-yl)pyrimidin-4-yl)-2-(2-chlorophenyl)acetamide (CAS 1448130-33-3)
- N-(4-Chlorobenzyl)-2-oxo-1,2-dihydro-1,8-naphthyridine-3-carboxamide (CAS 1467691-86-6)
- Methyl 2-(4-chlorophenyl)-5-phenyloxazole-4-carboxylate (CAS 1370731-53-5)
- N-(Benzo[d][1,3]dioxol-5-ylmethyl)-6-chloroquinazolin-4-amine (CAS 150450-53-6)
- 1,1,3-Trimethyl-3-(piperidin-4-yl)urea (CAS 70724-85-5)
- 1-(2,4-Difluorophenyl)-3-(pyridin-2-ylsulfanyl)pyrrolidine-2,5-dione (CAS 329078-72-0)
- 6-Methoxy[1,5]naphthyridine-4-carbaldehyde (CAS 881657-74-5)
- Tert-butyl (2-amino-2-oxoethyl)(tert-butyl)carbamate (CAS 1935293-14-3)
- 2-(4-(Difluoromethyl)benzo[d]oxazol-2-yl)acetic acid (CAS 1806303-61-6)
- Methyl Formate-d1 (CAS 23731-38-6)
- Zoledronic Acid EP Impurity A (CAS 1627731-60-5)
- 2-(1H-Imidazol-1-yl)ethyl methyl carbonate (CAS 798571-50-3)
- 2,5-Diaminopyrimidin-4(3H)-one sulfate (CAS 127726-94-7)
- Semaglutide impurity 101 (CAS CATO-C4X-2226101)
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