5-Bromo-2-methyl-1-(phenylsulfonyl)-4-azaindole CAS 1448259-50-4
| CAS No. | 1448259-50-4 |
| Molecular Formula | C14H11BrN2O2S |
| Molecular Weight | 351.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 5-Bromo-2-methyl-1-(phenylsulfonyl)-4-azaindole (C14H11BrN2O2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
5-Bromo-2-methyl-1-(phenylsulfonyl)-4-azaindole (CAS 1448259-50-4), molecular formula C14H11BrN2O2S and molecular weight 351.22 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 5-Bromo-2-methyl-1-(phenylsulfonyl)-4-azaindole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H11BrN2O2S |
| Molecular Weight | 351.22 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Bromo Standards
- 4-Bromo-2-methyl-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine (CAS 1014613-05-8)
- 3-Bromo-1-tosyl-1H-pyrrolo[3,2-b]pyridine (CAS 1060813-00-4)
- 5-bromo-2-methyl-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine (CAS 1111638-01-7)
- 2-Bromo-1-tosyl-1H-pyrrolo[2,3-b]pyridine (CAS 1198416-32-8)
- 2-Bromo-5-methyl-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine (CAS 1227268-83-8)
- 5-Bromo-6-methyl-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine (CAS 1227270-75-8)
- 5-Bromo-4-methyl-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine (CAS 1227270-76-9)
- Ethyl 5-bromo-2-((tert-butoxycarbonyl)amino)thiazole-4-carboxylate (CAS 1279863-32-9)
Recommended Standards
- 6-Bromo-2-methyl-1-(phenylsulfonyl)-1H-pyrrolo[3,2-b]pyridine (CAS 1427503-34-1)
- tert-Butyl (1r,4r)-4-((Z)-2-iodovinyl)-cyclohexylcarbamate (CAS 1452485-43-6)
- Ethyl 2-bromo-5-((tert-butoxycarbonyl)amino)thiazole-4-carboxylate (CAS 1395284-70-4)
- Tert-butyl (2-bromo-4-sulfamoylphenyl)carbamate (CAS 1477864-22-4)
- N-(1-(1H-Imidazol-2-yl)ethyl)-N-methylfuran-2-amine (CAS 875917-43-4)
- 5-Bromo-4,6-dihydrazinylpyrimidine (CAS 825-49-0)
- {2-[(4-methylphenyl)sulfanyl]pyridin-3-yl}methyl N-(3-chlorophenyl)carbamate (CAS 478031-16-2)
- (1-(4-Chlorophenyl)-1H-1,2,3-triazol-4-yl)methyl (4-chlorophenyl)carbamate (CAS 338419-14-0)
- N'-(1-(3-aminophenyl)ethylidene)-3-phenylpropanehydrazide (CAS 303768-48-1)
- tert-butyl p-tolylcarbamate (CAS 14618-59-8)
- 1-(2-Methylthiazole-4-carbonyl)piperidine-3-carboxylic acid (CAS 1486726-11-7)
- (Z)-2-(3-methoxyphenyl)-3-(6-(piperidin-1-yl)pyridin-3-yl)acrylonitrile (CAS 866019-91-2)
- 5-Methyl-2-(trifluoromethyl)benzonitrile (CAS 886502-61-0)
- Allo-Thr5-Tirzepatide (CAS CATO-CPTD788934)
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