Argatroban Impurity 10 CAS 1448301-07-2
| CAS No. | 1448301-07-2 |
| Molecular Formula | C23H35N7O7S |
| Molecular Weight | 553.63 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Argatroban Impurity 10 (C23H35N7O7S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a process- or degradation-related impurity, Argatroban Impurity 10 (CAS 1448301-07-2, C23H35N7O7S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H35N7O7S |
| Molecular Weight | 553.63 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Nitrogen Atoms | 7 |
| Sulfur Atoms | 1 |
Related Argatroban Standards
- Argatroban Impurity 145 (CAS CATO-C4X-1007145)
- Argatroban Impurity 133 (CAS CATO-C4X-1007133)
- Argatroban Impurity 24 (CAS 74874-10-5)
- Argatroban Impurity 57 (CAS CATO-C4X-100757)
- Argatroban Impurity 58 (CAS CATO-C4X-100758)
- Argatroban Impurity 59 (CAS CATO-C4X-100759)
- Argatroban Impurity 60 (CAS 450368-56-6)
- Argatroban Impurity 103 (CAS CATO-C4X-1007103)
Recommended Standards
- Fmoc-Tyr(SO2(ONeopentyl))-OH (CAS 878408-63-0)
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- Cefcapene Impurity 76 (CAS CATO-C4X-182476)
- N-{[4-(Benzyloxy)phenyl]methyl}-N-[(3-fluorophenyl)methyl]-4-phenoxybenzene-1-sulfonamide (CAS 1253528-00-5)
- Iguratimod Impurity 109 (CAS CATO-C4X-1826109)
- Avibactam Impurity 160 (CAS CATO-C4X-1348160)
- Ticagrelor Impurity 176 (CAS CATO-C4X-1093176)
- (R)-7-isopropyltetrahydro-1H-oxazolo[3,4-a]pyrazin-3(5H)-one (CAS 1795787-32-4)
- Cyclohexyl-n-hexyl-β-D-maltoside (CAS 228579-27-9)
- 1,9-Dichlorononane (CAS 821-99-8)
- 2-(4-Methoxyphenoxy)quinoxaline (CAS 338394-64-2)
- Ethyl 3-acetyl-1H-indole-2-carboxylate (CAS 77069-10-4)
- Ursodeoxycholic Acid impurity 93 (CAS CATO-C4X-142293)
- Tirzepatide Impurity 36 (CAS CATO-C4X-324036)
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