2�-Deoxy-5�-O-tritylthymidine-3�-O-N,N-diisopropylaminocyanoethylphosphoramidite CAS 144845-97-6

Purity 97%+In StockPharmaceutical Standards
CAS No.144845-97-6
Molecular FormulaC38H45N4O6P
Molecular Weight684.76 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2�-Deoxy-5�-O-tritylthymidine-3�-O-N,N-diisopropylaminocyanoethylphosphoramidite CAS 144845-97-6 chemical structure

Description

Based on its molecular formula C38H45N4O6P, 2�-Deoxy-5�-O-tritylthymidine-3�-O-N,N-diisopropylaminocyanoethylphosphoramidite contains a nitrogen-containing heterocyclic scaffold, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 684.76 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

2�-Deoxy-5�-O-tritylthymidine-3�-O-N,N-diisopropylaminocyanoethylphosphoramidite (CAS 144845-97-6), molecular formula C38H45N4O6P and molecular weight 684.76 g/mol, is a CATO reference standard with documented purity and traceability.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC38H45N4O6P
Molecular Weight684.76 g/mol
Purity97%+
StorageStore in a cool place (≤25°C), protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)18.5
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1998
Nitrogen Atoms4

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