tert-Butyl (2-iodo-5-(trifluoromethyl)phenyl)carbamate CAS 1448535-57-6
| CAS No. | 1448535-57-6 |
| Molecular Formula | C12H13F3INO2 |
| Molecular Weight | 387.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
tert-Butyl (2-iodo-5-(trifluoromethyl)phenyl)carbamate (C12H13F3INO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/iodine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
tert-Butyl (2-iodo-5-(trifluoromethyl)phenyl)carbamate (CAS 1448535-57-6), molecular formula C12H13F3INO2 and molecular weight 387.14 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures tert-Butyl (2-iodo-5-(trifluoromethyl)phenyl)carbamate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H13F3INO2 |
| Molecular Weight | 387.14 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F/I-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- tert-Butyl (2-iodo-4-(trifluoromethyl)phenyl)carbamate (CAS 1260642-67-8)
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- tert-Butyl 2-amino-5-iodo-4-(trifluoromethyl)benzoate (CAS 1131587-56-8)
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- tert-butyl 3-(2-hydroxyethyl)-3-methyl-azetidine-1-carboxylate (CAS 2306270-35-7)
- 2-Nitro-5-(piperidin-1-yl)pyridine (CAS 444146-17-2)
- C-Peptide (human) (CAS 33017-11-7)
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