N-(Piperidin-4-yl)pyrazin-2-amine dihydrochloride CAS 1448854-99-6
| CAS No. | 1448854-99-6 |
| Molecular Formula | C9H14N4 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
N-(Piperidin-4-yl)pyrazin-2-amine dihydrochloride (CAS 1448854-99-6), molecular formula C9H14N4HCl and molecular weight 214.70 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution, N-(Piperidin-4-yl)pyrazin-2-amine dihydrochloride is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 214.70 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H14N4 2*HCl |
| Molecular Weight | 214.70 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related N Standards
- 1000339-76-3 Ethyl 2-(Piperidin-1-yl)-4-(trifluoromethyl)-1,3-thiazole-5-carboxylate ethyl 2-(piperidin-1-yl)-4-trifluoromethyl-1,3-thiazole-5-carboxylate ethyl 2-piperidin-1-yl-4-(trifluoromethyl)-1,3-thiazole-5-carboxylate (CAS 1000339-76-3)
- 2-(Piperidin-1-yl)-4-(trifluoromethyl)thiazole-5-carboxylic acid (CAS 1000339-77-4)
- Benzyl 2-(piperidin-4-yl)acetate hydrochloride (CAS 1000872-47-8)
- n-(Piperidin-3-ylmethyl)morpholine-4-carboxamide (CAS 1000941-33-2)
- 1000958-55-3 4-Ethyl-1-[2-(piperidin-4-yl)ethyl]piperidine DTXSID60649257 (CAS 1000958-55-3)
- 5-(Piperidin-2-yl)pyridin-2-amine (CAS 100133-12-8)
- 5-(Piperidin-1-ylmethyl)pyrimidine-2,4(1H,3H)-dione (CAS 100133-53-7)
- 1-methyl-5-(piperidin-1-ylcarbonyl)-1H-pyrazol-4-amine (CAS 1001500-82-8)
Recommended Standards
- (8S,9S,10R,13S,14S)-10,13-dimethyl-7-oxo-1,2,3,4,7,8,9,10,11,12,13,14,15,16-tetradecahydrospiro[cyclopenta[a]phenanthrene-17,2'-[1,3]dioxolan]-3-yl acetate (CAS 40573-86-2)
- Benzyl N-(pyrrolidin-3-ylmethyl)carbamate (CAS 1038350-84-3)
- 4-(2,5-Dimethyl-1H-pyrrol-1-yl)pyridine (CAS 5044-29-1)
- -cyano-N-[(3,4-dimethoxyphenyl)methyl]methanesulfonamide (CAS 951399-50-1)
- Acetylcarbonyl(eta5-2,4-cyclopentadien-1-yl)(triphenylphosphine)iron (CAS 36548-61-5)
- 5-Bromofuro[2,3-d]pyrimidin-4-amine (CAS 1211525-35-7)
- N-((5-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)isoxazol-3-yl)methyl)-2-(thiophen-2-yl)acetamide (CAS 1210355-64-8)
- 4-Bromo-2-(difluoromethyl)-3-iodopyridine (CAS 1806763-77-8)
- 2-Methyl-5H-[1,3]dioxolo[4,5-c]pyrrole (CAS 259796-65-1)
- Semaglutide Impurity 8 (CAS CATO-C4X-22268)
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