3-(4-Fluorophenyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrimidine CAS 1448855-47-7
| CAS No. | 1448855-47-7 |
| Molecular Formula | C11H11FN4 |
| Molecular Weight | 218.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-(4-Fluorophenyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrimidine (C11H11FN4) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
3-(4-Fluorophenyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrimidine (CAS 1448855-47-7) is a high-purity analytical reference standard with the molecular formula C11H11FN4 and a molecular weight of 218.23 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-(4-Fluorophenyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrimidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H11FN4 |
| Molecular Weight | 218.23 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Fluorophenyl Standards
- 1-[(4-Fluorophenyl)methyl]-5-oxopyrrolidine-3-carbonitrile (CAS 1017397-80-6)
- 1-(2-Fluorophenyl)-3,5-dimethyl-1h-pyrazole-4-carbaldehyde (CAS 1134946-79-4)
- 3-(2-Fluorophenyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine (CAS 1159530-94-5)
- 3-(4-Fluorophenyl)-4,5,6,7-tetrahydroisoxazolo[4,5-c]pyridine (CAS 1188264-00-7)
- 5-[2-(4-fluorophenyl)ethenyl]-3-methyl-1,2-oxazol-4-amine (CAS 1235441-81-2)
- 2-(4-Fluorophenyl)-1-(1-methyl-1h-imidazol-2-yl)ethan-1-one (CAS 1343304-63-1)
- 3-(3-Fluorophenyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrimidine (CAS 1448854-61-2)
- 3-(2-Fluorophenyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrimidine (CAS 1448854-89-4)
Recommended Standards
- 1-cyano-N-[(2-fluorophenyl)methyl]cyclopropane-1-carboxamide (CAS 1511939-66-4)
- 1-(6-Fluoropyridin-3-yl)-4-oxocyclohexane-1-carbonitrile (CAS 1600498-50-7)
- 3,5-Dimethyl-4-sulfamoyl-1h-pyrrole-2-carboxylic acid (CAS 1394041-61-2)
- Methyl 2-amino-3-(2,4-dioxothiazolidin-3-yl)propanoate (CAS 1706429-76-6)
- 2,5-Di(piperidin-1-yl)aniline (CAS 1018619-00-5)
- Methyl 3-[(butan-2-yl)amino]-2-methylpropanoate (CAS 53118-64-2)
- (R)-1-(4-fluoro-3-methoxyphenyl)butan-1-amine (CAS 1213534-62-3)
- 3-Fluoro-4-methyl-5-(trifluoromethyl)benzenesulfonyl chloride (CAS 1706451-99-1)
- methyl[2-({5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}oxy)ethyl]amine (CAS 1250173-02-4)
- Ethyl 2-amino-5-ethyloxazole-4-carboxylate (CAS 2101425-38-9)
- Ac-KQLR-AFC Trifluoroacetate (CAS 1802078-38-1)
- 2,5,8,11,14,17,20,23,26-Nonaoxaheptacosane (CAS 25990-94-7)
- Abiraterone N-oxide Sulfate (CAS 1993430-24-2)
- Custom peptides (CAS CATO-CPTD788509)
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