2-(4-Bromo-5-methoxypyridin-2-yl)acetonitrile CAS 1448870-49-2
| CAS No. | 1448870-49-2 |
| Molecular Formula | C8H7BrN2O |
| Molecular Weight | 227.06 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies 2-(4-Bromo-5-methoxypyridin-2-yl)acetonitrile (CAS 1448870-49-2), a certified reference material (molecular formula C8H7BrN2O, MW 227.06 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution, 2-(4-Bromo-5-methoxypyridin-2-yl)acetonitrile is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 227.06 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C8H7BrN2O |
| Molecular Weight | 227.06 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Related Bromo Standards
- 3-Bromo-5-methoxy-1H-pyrrolo[3,2-b]pyridine (CAS 1000341-09-2)
- 3-Bromo-4-methoxy-1H-pyrrolo[3,2-c]pyridine (CAS 1000341-22-9)
- 6-Bromo-4-methoxy-1H-pyrrolo[3,2-c]pyridine (CAS 1000342-81-3)
- 5-Bromo-6-methoxy-1H-benzo[d]imidazole (CAS 1008361-65-6)
- 4-Bromo-5-methoxy-1H-benzo[d]imidazole (CAS 1008361-66-7)
- 7-Bromo-3,4-dihydroquinoxalin-2(1H)-one (CAS 1016878-52-6)
- 3-Bromo-4-methoxy-1H-pyrrolo[2,3-b]pyridine (CAS 1053655-78-9)
- 8-Bromo-3,4-dihydroquinoxalin-2(1H)-one (CAS 1092563-81-9)
Recommended Standards
- 3-Bromo-1-methyl-1H-indazol-5-ol (CAS 1446407-67-5)
- 6-Bromo-2-methoxy-1H-benzo[d]imidazole (CAS 1502338-01-3)
- 2-Amino-3-bromo-6-methoxybenzonitrile (CAS 1440526-35-1)
- 6-Bromo-2-methylimidazo[1,2-a]pyrimidin-3-amine (CAS 1505861-73-3)
- N-Acetyl-O-ethylhydroxylamine (CAS 52914-24-6)
- 6-Amino-2-bromo-3-iodobenzoic acid (CAS 2089649-07-8)
- 6-(4-Methoxyphenyl)-2-phenylpyrazolo[1,5-a]pyrimidine (CAS 893613-49-5)
- 2-(6-Bromo-3-(difluoromethyl)-5-hydroxypyridin-2-yl)acetonitrile (CAS 1805408-76-7)
- 2-(2,2-Dibromovinyl)furan (CAS 100074-10-0)
- 1-[2-(1H-pyrazol-1-yl)ethyl]-1H-pyrazole-3-carboxylic acid (CAS 1341921-76-3)
- 2-cyclohexylethane-1-sulfonamide (CAS 4378-98-7)
- 5-Bromo-6-chloroquinoxaline (CAS 1858756-03-2)
- Dapagliflozin Impurity 210 (CAS CATO-C4X-1138210)
- Ganirelix 1-4 peptide (CAS 208599-57-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com